U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Larp1b La ribonucleoprotein 1B [ Mus musculus (house mouse) ]

Gene ID: 214048, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Larp1bprovided by MGI
Official Full Name
La ribonucleoprotein 1Bprovided by MGI
Primary source
MGI:MGI:1914604
See related
Ensembl:ENSMUSG00000025762 AllianceGenome:MGI:1914604
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Larp2; 1700108L22Rik; 4933421B21Rik
Summary
Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of translation. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human LARP1B (La ribonucleoprotein 1B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 7.9), small intestine adult (RPKM 2.9) and 25 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
3 B; 3 19.61 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (40904198..40994642)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (40949770..41040207)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6430590A07 gene Neighboring gene abhydrolase domain containing 18 Neighboring gene FUN14 domain containing 2B Neighboring gene STARR-positive B cell enhancer ABC_E7910 Neighboring gene STARR-seq mESC enhancer starr_07475 Neighboring gene predicted gene, 22043 Neighboring gene predicted gene 42437 Neighboring gene STARR-seq mESC enhancer starr_07477 Neighboring gene STARR-positive B cell enhancer mm9_chr3:40886815-40887116 Neighboring gene progesterone receptor membrane component 2 Neighboring gene STARR-seq mESC enhancer starr_07478 Neighboring gene STARR-seq mESC enhancer starr_07480 Neighboring gene STARR-seq mESC enhancer starr_07481 Neighboring gene predicted gene, 40038

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
  2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • FLJ10378, MGC38253, MGC117760

General protein information

Go to the top of the page Help
Preferred Names
la-related protein 1B
Names
La ribonucleoprotein domain family, member 1B
La ribonucleoprotein domain family, member 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040399.3 → NP_001035489.2  la-related protein 1B isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC102794
    UniProtKB/TrEMBL
    F6U5V1
    Related
    ENSMUSP00000037127.8, ENSMUST00000048490.13
    Conserved Domains (1) summary
    cd08038
    Location:422 → 494
    LARP_2; La RNA-binding domain of La-related protein 2

  2. NM_001368221.1 → NP_001355150.1  la-related protein 1B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC102794
    Consensus CDS
    CCDS38423.1
    UniProtKB/TrEMBL
    A0A0A6YWC2, Q8BVS5
    Related
    ENSMUSP00000141487.2, ENSMUST00000191805.7
    Conserved Domains (1) summary
    cd08038
    Location:216 → 288
    LARP_2; La RNA-binding domain of La-related protein 2

  3. NM_001368222.1 → NP_001355151.1  la-related protein 1B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC102794
    Consensus CDS
    CCDS89623.1
    UniProtKB/TrEMBL
    Q3TQS1, Q8BVS5
    Related
    ENSMUSP00000142106.2, ENSMUST00000191872.6

  4. NM_001394999.1 → NP_001381928.1  la-related protein 1B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC102794
    UniProtKB/TrEMBL
    A0A0A6YWC2, Q8BVS5
    Conserved Domains (1) summary
    cd08038
    Location:216 → 288
    LARP_2; La RNA-binding domain of La-related protein 2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    40904198..40994642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163009.1 → XP_036018902.1  la-related protein 1B isoform X3

  2. XM_036163004.1 → XP_036018897.1  la-related protein 1B isoform X1

    UniProtKB/TrEMBL
    F6U5V1
    Conserved Domains (1) summary
    cd08038
    Location:422 → 494
    LARP_2; La RNA-binding domain of La-related protein 2

  3. XM_036163005.1 → XP_036018898.1  la-related protein 1B isoform X1

    UniProtKB/TrEMBL
    F6U5V1
    Conserved Domains (1) summary
    cd08038
    Location:422 → 494
    LARP_2; La RNA-binding domain of La-related protein 2

  4. XM_030252544.2 → XP_030108404.2  la-related protein 1B isoform X1

    UniProtKB/TrEMBL
    F6U5V1
    Conserved Domains (1) summary
    cd08038
    Location:422 → 494
    LARP_2; La RNA-binding domain of La-related protein 2

  5. XM_036163006.1 → XP_036018899.1  la-related protein 1B isoform X1

    UniProtKB/TrEMBL
    F6U5V1
    Conserved Domains (1) summary
    cd08038
    Location:422 → 494
    LARP_2; La RNA-binding domain of La-related protein 2

  6. XM_036163008.1 → XP_036018901.1  la-related protein 1B isoform X2

    UniProtKB/TrEMBL
    A0A0A6YWC2, Q8BVS5
    Conserved Domains (1) summary
    cd08038
    Location:216 → 288
    LARP_2; La RNA-binding domain of La-related protein 2

  7. XM_036163007.1 → XP_036018900.1  la-related protein 1B isoform X2

    UniProtKB/TrEMBL
    A0A0A6YWC2, Q8BVS5
    Conserved Domains (1) summary
    cd08038
    Location:216 → 288
    LARP_2; La RNA-binding domain of La-related protein 2

  8. XM_036163010.1 → XP_036018903.1  la-related protein 1B isoform X4

    UniProtKB/TrEMBL
    Q9D423
    Conserved Domains (1) summary
    smart00684
    Location:119 → 157
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function

  9. XM_036163011.1 → XP_036018904.1  la-related protein 1B isoform X5

    UniProtKB/TrEMBL
    Q9D423
    Related
    ENSMUSP00000096721.4, ENSMUST00000099121.10
    Conserved Domains (1) summary
    smart00684
    Location:119 → 157
    DM15; Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_027663.1: Suppressed sequence

    Description
    NM_027663.1: This RefSeq was suppressed temporarily because it represents a fragment of an Larp2 mRNA.

  2. NM_145988.1: Suppressed sequence

    Description
    NM_145988.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous