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Map9 microtubule-associated protein 9 [ Mus musculus (house mouse) ]

Gene ID: 213582, updated on 5-Mar-2024

Summary

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Official Symbol
Map9provided by MGI
Official Full Name
microtubule-associated protein 9provided by MGI
Primary source
MGI:MGI:2442208
See related
Ensembl:ENSMUSG00000033900 AllianceGenome:MGI:2442208
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ASAP; Mtap9; 5033421J10Rik; 5330427D05Rik
Summary
Predicted to enable microtubule binding activity. Acts upstream of or within mitotic spindle assembly. Located in astral microtubule and mitotic spindle midzone. Orthologous to human MAP9 (microtubule associated protein 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 17.3), cortex adult (RPKM 9.4) and 9 other tissues See more
Orthologs
human all
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Genomic context

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See Map9 in Genome Data Viewer
Location:
3 E3; 3 36.37 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (82265379..82302575)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (82358072..82395268)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 29921 Neighboring gene STARR-seq mESC enhancer starr_08033 Neighboring gene predicted gene, 57713 Neighboring gene STARR-seq mESC enhancer starr_08035 Neighboring gene STARR-positive B cell enhancer mm9_chr3:82161796-82162097 Neighboring gene STARR-seq mESC enhancer starr_08038 Neighboring gene neuropeptide Y receptor Y2 Neighboring gene predicted gene, 29999

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Gene organization, evolution and expression of the microtubule-associated protein ASAP (MAP9). Venoux M, et al. BMC Genomics, 2008 Sep 9. PMID 18782428, Free PMC Article
  2. MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer. Wang S, et al. Clin Cancer Res, 2020 Feb 1. PMID 31662330
  3. Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry. Del Mar Masdeu M, et al. Oncotarget, 2017 Nov 24. PMID 29254152, Free PMC Article
  4. The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue. Martins-de-Souza D, et al. Proteomics Clin Appl, 2015 Oct. PMID 25921334
  5. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.
    Title: MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
  
involved_in mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mitotic spindle assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mitotic spindle assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of mitotic centrosome separation ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of mitotic cytokinesis ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of mitotic spindle organization ISO
Inferred from Sequence Orthology
more info
  
involved_in spindle assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in aster IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in astral microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in astral microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in astral microtubule ISO
Inferred from Sequence Orthology
more info
  
located_in axon ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule cytoskeleton IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitotic spindle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
  
located_in mitotic spindle midzone IDA
Inferred from Direct Assay
more info
 PubMed 
located_in spindle midzone ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
microtubule-associated protein 9
Names
aster-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081230.1 → NP_001074699.1  microtubule-associated protein 9

    See identical proteins and their annotated locations for NP_001074699.1

    Status: VALIDATED

    Source sequence(s)
    AC126248, AC126557
    Consensus CDS
    CCDS38461.1
    UniProtKB/Swiss-Prot
    Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7
    UniProtKB/TrEMBL
    A0A0A6YXJ3
    Related
    ENSMUSP00000088535.5, ENSMUST00000091014.10
    Conserved Domains (1) summary
    PTZ00121
    Location:445 → 622
    PTZ00121; MAEBL; Provisional

  2. NM_001356457.1 → NP_001343386.1  microtubule-associated protein 9

    Status: VALIDATED

    Source sequence(s)
    AC126248, AC126557, AK147287
    Consensus CDS
    CCDS38461.1
    UniProtKB/Swiss-Prot
    Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7
    UniProtKB/TrEMBL
    A0A0A6YXJ3
    Related
    ENSMUSP00000142206.2, ENSMUST00000195640.2
    Conserved Domains (1) summary
    PTZ00121
    Location:445 → 622
    PTZ00121; MAEBL; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    82265379..82302575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252539.2 → XP_030108399.1  microtubule-associated protein 9 isoform X1

    UniProtKB/Swiss-Prot
    Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7
    UniProtKB/TrEMBL
    A0A0A6YXJ3
    Conserved Domains (1) summary
    PTZ00121
    Location:445 → 622
    PTZ00121; MAEBL; Provisional

  2. XM_030252540.2 → XP_030108400.1  microtubule-associated protein 9 isoform X1

    UniProtKB/Swiss-Prot
    Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7
    UniProtKB/TrEMBL
    A0A0A6YXJ3
    Conserved Domains (1) summary
    PTZ00121
    Location:445 → 622
    PTZ00121; MAEBL; Provisional
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TRR0.2 GenPept UniProtKB/Swiss-Prot:Q3TRR0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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