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Tent5d terminal nucleotidyltransferase 5D [ Mus musculus (house mouse) ]

Gene ID: 213449, updated on 5-Mar-2024

Summary

Official Symbol
Tent5dprovided by MGI
Official Full Name
terminal nucleotidyltransferase 5Dprovided by MGI
Primary source
MGI:MGI:2685223
See related
Ensembl:ENSMUSG00000073007 AllianceGenome:MGI:2685223
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm377; Fam46d
Summary
Predicted to enable RNA adenylyltransferase activity. Predicted to be involved in mRNA stabilization. Orthologous to human TENT5D (terminal nucleotidyltransferase 5D). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 2.0) See more
Orthologs
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Genomic context

Location:
X D; X 47.62 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (106836196..106916517)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (107792590..107872911)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene GLE1 RNA export mediator pseudogene Neighboring gene STARR-seq mESC enhancer starr_47746 Neighboring gene STARR-seq mESC enhancer starr_47747 Neighboring gene T-box 22 Neighboring gene STARR-seq mESC enhancer starr_47748 Neighboring gene charged multivesicular body protein 1B2 Neighboring gene STARR-seq mESC enhancer starr_47749 Neighboring gene STARR-seq mESC enhancer starr_47750 Neighboring gene STARR-seq mESC enhancer starr_47751 Neighboring gene WAVE homology in membrane protrusions Neighboring gene STARR-seq mESC enhancer starr_47752 Neighboring gene MYST histone acetyltransferase (monocytic leukemia) 3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables poly(A) RNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables poly(A) RNA polymerase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in mRNA stabilization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
terminal nucleotidyltransferase 5D
Names
family with sequence similarity 46, member D
NP_001156576.1
NP_001257937.1
XP_006527999.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163104.2NP_001156576.1  terminal nucleotidyltransferase 5D

    See identical proteins and their annotated locations for NP_001156576.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK133246, AL669851, BB865956
    Consensus CDS
    CCDS53172.1
    UniProtKB/TrEMBL
    B1ATX6
    Related
    ENSMUSP00000129483.2, ENSMUST00000167154.2
    Conserved Domains (1) summary
    pfam07984
    Location:9326
    NTP_transf_7; Nucleotidyltransferase
  2. NM_001271008.1NP_001257937.1  terminal nucleotidyltransferase 5D

    See identical proteins and their annotated locations for NP_001257937.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK133246, AL669851
    Consensus CDS
    CCDS53172.1
    UniProtKB/TrEMBL
    B1ATX6
    Related
    ENSMUSP00000098850.3, ENSMUST00000101292.9
    Conserved Domains (1) summary
    pfam07984
    Location:9326
    NTP_transf_7; Nucleotidyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    106836196..106916517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527936.2XP_006527999.1  terminal nucleotidyltransferase 5D isoform X1

    See identical proteins and their annotated locations for XP_006527999.1

    UniProtKB/TrEMBL
    B1ATX6
    Conserved Domains (1) summary
    pfam07984
    Location:9326
    NTP_transf_7; Nucleotidyltransferase