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Rassf4 Ras association (RalGDS/AF-6) domain family member 4 [ Mus musculus (house mouse) ]

Gene ID: 213391, updated on 11-Apr-2024

Summary

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Official Symbol
Rassf4provided by MGI
Official Full Name
Ras association (RalGDS/AF-6) domain family member 4provided by MGI
Primary source
MGI:MGI:2386853
See related
Ensembl:ENSMUSG00000042129 AllianceGenome:MGI:2386853
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AD037; 3830411C14Rik
Summary
Predicted to be involved in signal transduction. Is expressed in nasal cavity epithelium; nervous system; and neural retina. Orthologous to human RASSF4 (Ras association domain family member 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in mammary gland adult (RPKM 9.8), spleen adult (RPKM 8.6) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
6 E3; 6 53.83 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (116609969..116650797, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (116633008..116673836, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene crumbs homolog 1 pseudogene Neighboring gene zinc finger protein 422 Neighboring gene STARR-seq mESC enhancer starr_17106 Neighboring gene STARR-positive B cell enhancer ABC_E6474 Neighboring gene microRNA 7043 Neighboring gene DEPP1 autophagy regulator Neighboring gene STARR-positive B cell enhancer ABC_E2202 Neighboring gene STARR-positive B cell enhancer mm9_chr6:116632394-116632695 Neighboring gene transmembrane protein 72 Neighboring gene predicted gene, 22882

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. Lai HC, et al. J Neurosci, 2011 Jul 27. PMID 21795538, Free PMC Article
  2. Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification. Stylianou IM, et al. Genetics, 2008 Mar. PMID 18245842, Free PMC Article
  3. The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Ray JP, et al. Immunity, 2015 Oct 20. PMID 26410627, Free PMC Article
  4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
ras association domain-containing protein 4
Names
Ras association (RalGDS/AF-6) domain family 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178045.4 → NP_835146.3  ras association domain-containing protein 4

    See identical proteins and their annotated locations for NP_835146.3

    Status: VALIDATED

    Source sequence(s)
    AC160973, AK036528, BC060709, BY170346
    Consensus CDS
    CCDS20460.1
    UniProtKB/Swiss-Prot
    Q3TBK1, Q3TPH9, Q3TUT0, Q6P9L7, Q8CB96, Q8CIM6
    Related
    ENSMUSP00000048267.5, ENSMUST00000035842.7
    Conserved Domains (1) summary
    cl00155
    Location:176 → 262
    UBQ; Ubiquitin-like proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    116609969..116650797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505866.5 → XP_006505929.1  ras association domain-containing protein 4 isoform X1

    Conserved Domains (2) summary
    PHA03309
    Location:60 → 163
    PHA03309; transcriptional regulator ICP4; Provisional
    cd17222
    Location:151 → 237
    RA_RASSF4; Ras-associating (RA) domain found in Ras-association domain-containing protein 4 (RASSF4)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CB96.1 GenPept UniProtKB/Swiss-Prot:Q8CB96

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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