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Gatd1 glutamine amidotransferase like class 1 domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 213350, updated on 5-Mar-2024

Summary

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Official Symbol
Gatd1provided by MGI
Official Full Name
glutamine amidotransferase like class 1 domain containing 1provided by MGI
Primary source
MGI:MGI:2387178
See related
Ensembl:ENSMUSG00000051007 AllianceGenome:MGI:2387178
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pddc1; D230016J19Rik
Summary
Predicted to be located in extracellular region. Orthologous to human GATD1 (glutamine amidotransferase class 1 domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 47.2), genital fat pad adult (RPKM 37.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 F5; 7 86.75 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (140988097..140994038, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (141408184..141414125, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8223 Neighboring gene transaldolase 1 Neighboring gene RAN guanine nucleotide release factor pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3761 Neighboring gene cell cycle exit and neuronal differentiation 1 Neighboring gene solute carrier family 25 (mitochondrial carrier, glutamate), member 22 Neighboring gene STARR-positive B cell enhancer ABC_E4986

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue. Martins-de-Souza D, et al. Proteomics Clin Appl, 2015 Oct. PMID 25921334
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC38368

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glyoxalase III activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutamine amidotransferase-like class 1 domain-containing protein 1
Names
Parkinson disease 7 domain containing 1
parkinson disease 7 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172116.4 → NP_742114.3  glutamine amidotransferase-like class 1 domain-containing protein 1 precursor

    See identical proteins and their annotated locations for NP_742114.3

    Status: VALIDATED

    Source sequence(s)
    AK081187, AK084273, AK140975, BY118625
    Consensus CDS
    CCDS52444.1
    UniProtKB/Swiss-Prot
    Q8BFQ8, Q8C2Q9
    Related
    ENSMUSP00000101630.2, ENSMUST00000106008.3
    Conserved Domains (2) summary
    cd03141
    Location:12 → 216
    GATase1_Hsp31_like; Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein
    COG0693
    Location:31 → 204
    ThiJ; Putative intracellular protease/amidase [General function prediction only]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    140988097..140994038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006536171.3 → XP_006536234.2  glutamine amidotransferase-like class 1 domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    cd03141
    Location:12 → 201
    GATase1_Hsp31_like; Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BFQ8.1 GenPept UniProtKB/Swiss-Prot:Q8BFQ8

Gene LinkOut

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