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Zbbx zinc finger, B-box domain containing [ Mus musculus (house mouse) ]

Gene ID: 213234, updated on 3-Apr-2024

Summary

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Official Symbol
Zbbxprovided by MGI
Official Full Name
zinc finger, B-box domain containingprovided by MGI
Primary source
MGI:MGI:2674085
See related
Ensembl:ENSMUSG00000034151 AllianceGenome:MGI:2674085
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4931432L23
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in cilium movement. Predicted to be active in motile cilium. Is expressed in bladder; female associated reproductive structure; ovary; and urethra of female. Orthologous to human ZBBX (zinc finger B-box domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 21.6) See more
Orthologs
human all
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Genomic context

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Location:
3 E3; 3 33.72 cM
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (74945202..75072357, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (75037895..75165050, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_07965 Neighboring gene predicted gene, 36069 Neighboring gene STARR-seq mESC enhancer starr_07966 Neighboring gene 40S ribosomal protein S8 pseudogene Neighboring gene STARR-seq mESC enhancer starr_07968 Neighboring gene predicted gene, 40071 Neighboring gene serine (or cysteine) peptidase inhibitor, clade I, member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger B-box domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310529.2 → NP_001297458.1  zinc finger B-box domain-containing protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC121928, AC125332
    Consensus CDS
    CCDS79924.1
    UniProtKB/TrEMBL
    F8WIV1
    Related
    ENSMUSP00000043970.7, ENSMUST00000039269.13
    Conserved Domains (1) summary
    smart00336
    Location:13 → 58
    BBOX; B-Box-type zinc finger

  2. NM_001411534.1 → NP_001398463.1  zinc finger B-box domain-containing protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC121928, AC125332

  3. NM_172515.4 → NP_766103.2  zinc finger B-box domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_766103.2

    Status: VALIDATED

    Source sequence(s)
    AC121928, AC125332
    Consensus CDS
    CCDS17412.1
    UniProtKB/Swiss-Prot
    Q0P5X5, Q3V0J2
    Related
    ENSMUSP00000103407.3, ENSMUST00000107778.9
    Conserved Domains (1) summary
    smart00336
    Location:13 → 58
    BBOX; B-Box-type zinc finger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    74945202..75072357 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501258.1 → XP_006501321.1  zinc finger B-box domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    cd19818
    Location:132 → 174
    Bbox1_ZBBX; B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins

  2. XM_011240063.1 → XP_011238365.1  zinc finger B-box domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    cd19818
    Location:132 → 174
    Bbox1_ZBBX; B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins

  3. XM_006501257.1 → XP_006501320.1  zinc finger B-box domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    cd19818
    Location:132 → 174
    Bbox1_ZBBX; B-box-type 1 zinc finger found in zinc finger B-box domain-containing protein 1 (ZBBX) and similar proteins

  4. XM_036162996.1 → XP_036018889.1  zinc finger B-box domain-containing protein 1 isoform X5

  5. XM_011240064.2 → XP_011238366.1  zinc finger B-box domain-containing protein 1 isoform X6

    See identical proteins and their annotated locations for XP_011238366.1

  6. XM_011240065.2 → XP_011238367.1  zinc finger B-box domain-containing protein 1 isoform X6

    See identical proteins and their annotated locations for XP_011238367.1

RNA

  1. XR_003954303.1 RNA Sequence

  2. XR_004941300.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0P5X5.1 GenPept UniProtKB/Swiss-Prot:Q0P5X5

Gene LinkOut

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