U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ankrd35 ankyrin repeat domain 35 [ Mus musculus (house mouse) ]

Gene ID: 213121, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Ankrd35provided by MGI
Official Full Name
ankyrin repeat domain 35provided by MGI
Primary source
MGI:MGI:2442590
See related
Ensembl:ENSMUSG00000038354 AllianceGenome:MGI:2442590
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4732436F15Rik
Summary
Is expressed in 2-cell stage embryo; 4-cell stage embryo; anterior naris; and external naris. Orthologous to human ANKRD35 (ankyrin repeat domain 35). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 2.9), cerebellum adult (RPKM 1.9) and 21 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
3 F2.1; 3 41.94 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96577447..96598350)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96670131..96691034)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene integrin, alpha 10 Neighboring gene ribosomal protein L21, pseudogene 11 Neighboring gene STARR-positive B cell enhancer ABC_E6084 Neighboring gene STARR-seq mESC enhancer starr_08444 Neighboring gene protein inhibitor of activated STAT 3 Neighboring gene nudix hydrolase 17 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide C Neighboring gene predicted gene, 22581

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. In vitro selection of Jun-associated proteins using mRNA display. Horisawa K, et al. Nucleic Acids Res, 2004 Dec 2. PMID 15576676, Free PMC Article
  2. Deterministic and stochastic allele specific gene expression in single mouse blastomeres. Tang F, et al. PLoS One, 2011. PMID 21731673, Free PMC Article
  3. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ankyrin repeat domain-containing protein 35

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081139.1 → NP_001074608.1  ankyrin repeat domain-containing protein 35 isoform 1

    See identical proteins and their annotated locations for NP_001074608.1

    Status: VALIDATED

    Source sequence(s)
    AC112261
    Consensus CDS
    CCDS38558.1
    UniProtKB/TrEMBL
    A6H648, E9Q9D8
    Related
    ENSMUSP00000047244.6, ENSMUST00000048427.9
    Conserved Domains (4) summary
    cd00204
    Location:81 → 206
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:53 → 84
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:190 → 251
    Ank_2; Ankyrin repeats (3 copies)
    cl25732
    Location:710 → 996
    SMC_N; RecF/RecN/SMC N terminal domain

  2. NM_001356538.1 → NP_001343467.1  ankyrin repeat domain-containing protein 35 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC112261
    Consensus CDS
    CCDS38558.1
    UniProtKB/TrEMBL
    A6H648, E9Q9D8
    Conserved Domains (4) summary
    cd00204
    Location:81 → 206
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:53 → 84
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:190 → 251
    Ank_2; Ankyrin repeats (3 copies)
    cl25732
    Location:710 → 996
    SMC_N; RecF/RecN/SMC N terminal domain

  3. NM_001356539.1 → NP_001343468.1  ankyrin repeat domain-containing protein 35 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC112261
    UniProtKB/TrEMBL
    B7ZNG5
    Conserved Domains (3) summary
    PHA02875
    Location:7 → 164
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:659 → 945
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:35 → 66
    ANK; ANK repeat [structural motif]

  4. NM_001356540.1 → NP_001343469.1  ankyrin repeat domain-containing protein 35 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC112261, AK046624
    UniProtKB/TrEMBL
    B7ZNG5
    Conserved Domains (3) summary
    PHA02875
    Location:7 → 164
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:659 → 945
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:35 → 66
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    96577447..96598350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319516.2 → XP_017175005.1  ankyrin repeat domain-containing protein 35 isoform X1

    UniProtKB/TrEMBL
    B7ZNG5
    Conserved Domains (3) summary
    PHA02875
    Location:7 → 164
    PHA02875; ankyrin repeat protein; Provisional
    TIGR02168
    Location:659 → 945
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00045
    Location:35 → 66
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous