U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Bicdl2 BICD family like cargo adaptor 2 [ Mus musculus (house mouse) ]

Gene ID: 212733, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Bicdl2provided by MGI
Official Full Name
BICD family like cargo adaptor 2provided by MGI
Primary source
MGI:MGI:2388267
See related
Ensembl:ENSMUSG00000043782 AllianceGenome:MGI:2388267
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BICDR-2; Ccdc64b
Summary
Enables small GTPase binding activity. Predicted to be involved in Golgi to secretory granule transport and vesicle transport along microtubule. Orthologous to human BICDL2 (BICD family like cargo adaptor 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in colon adult (RPKM 5.0), stomach adult (RPKM 4.6) and 21 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
17 A3.3; 17 11.95 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (23863663..23887595)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23644605..23668621)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene calcium binding protein 39-like pseudogene Neighboring gene matrix metallopeptidase 25 Neighboring gene ribosomal protein L36 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8656 Neighboring gene THO complex 6 Neighboring gene host cell factor C1 regulator 1 (XPO1-dependent) Neighboring gene tumor necrosis factor receptor superfamily, member 12a Neighboring gene claudin 6

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis. Schlager MA, et al. EMBO J, 2010 May 19. PMID 20360680, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC47347

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables small GTPase binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi to secretory granule transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle transport along microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
BICD family-like cargo adapter 2
Names
BICD-related protein 2
bicaudal D-related protein 2
coiled-coil domain containing 64B
coiled-coil domain-containing protein 64B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153784.3 → NP_722479.1  BICD family-like cargo adapter 2

    See identical proteins and their annotated locations for NP_722479.1

    Status: VALIDATED

    Source sequence(s)
    AC154766, AK133729
    Consensus CDS
    CCDS28453.1
    UniProtKB/Swiss-Prot
    Q8CB50, Q8CHW5
    UniProtKB/TrEMBL
    A0A3B2WCI5
    Related
    ENSMUSP00000053808.9, ENSMUST00000062967.10
    Conserved Domains (2) summary
    TIGR02168
    Location:53 → 298
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:165 → 472
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    23863663..23887595
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249622.2 → XP_030105482.1  BICD family-like cargo adapter 2 isoform X2

    UniProtKB/Swiss-Prot
    Q8CB50, Q8CHW5
    UniProtKB/TrEMBL
    A0A3B2WCI5
    Conserved Domains (2) summary
    TIGR02168
    Location:53 → 298
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:165 → 472
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

  2. XM_006523985.5 → XP_006524048.1  BICD family-like cargo adapter 2 isoform X1

    UniProtKB/TrEMBL
    A0A3B2WCI5
    Related
    ENSMUSP00000156538.2, ENSMUST00000233541.2
    Conserved Domains (2) summary
    TIGR02168
    Location:36 → 254
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    TIGR02169
    Location:121 → 428
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CHW5.1 GenPept UniProtKB/Swiss-Prot:Q8CHW5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous