Tarbp1 TAR RNA binding protein 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tarbp1provided by MGI
Official Full Name: TAR RNA binding protein 1provided by MGI
Primary source: MGI:MGI:4936930
See related: Ensembl:ENSMUSG00000090290 AllianceGenome:MGI:4936930
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm179; Gm17296
Summary: Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Is expressed in cerebral cortex; heart; reproductive system; and thyroid gland. Orthologous to human TARBP1 (TAR (HIV-1) RNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in thymus adult (RPKM 2.7), ovary adult (RPKM 2.6) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 E2; 8 74.1 cM

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (127152053..127201837, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (126425314..126475098, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Binding of Dicer to TRBPs is critical for RNAi function.
Title: Characterization of the TRBP domain required for dicer interaction and function in RNA interference.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2)

General gene information

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Markers

PMC86057P1 (e-PCR)
- UniSTS:273513

TK1 (e-PCR)
- UniSTS:266729

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables tRNA (guanine) methyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in tRNA methylation	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: probable methyltransferase TARBP1

Names: TAR (HIV-1) RNA binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.