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Gm266 predicted gene 266 [ Mus musculus (house mouse) ]

Gene ID: 212539, updated on 8-Feb-2024

Summary

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Official Symbol
Gm266provided by MGI
Official Full Name
predicted gene 266provided by MGI
Primary source
MGI:MGI:2685112
See related
Ensembl:ENSMUSG00000010529 AllianceGenome:MGI:2685112
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Rap protein signal transduction and negative regulation of cell migration. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
12 F1; 12 61.01 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (111451043..111452257, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (111484609..111485823, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene exocyst complex component 3-like 4 Neighboring gene tumor necrosis factor, alpha-induced protein 2 Neighboring gene predicted gene, 40578 Neighboring gene STARR-positive B cell enhancer ABC_E138 Neighboring gene small nucleolar RNA, H/ACA box 28 Neighboring gene eukaryotic translation initiation factor 5 Neighboring gene RIKEN cDNA 2810029C07 gene Neighboring gene STARR-positive B cell enhancer ABC_E7187

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Georgas K, et al. Dev Biol, 2009 Aug 15. PMID 19501082
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GDP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Rap protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC212539

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033248.3 → NP_001028420.2  uncharacterized protein LOC212539

    See identical proteins and their annotated locations for NP_001028420.2

    Status: VALIDATED

    Source sequence(s)
    BC145736, BM898567
    Consensus CDS
    CCDS26179.1
    UniProtKB/TrEMBL
    A6H634, Q3TLP2
    Related
    ENSMUSP00000010673.6, ENSMUST00000010673.7
    Conserved Domains (2) summary
    smart00010
    Location:10 → 173
    small_GTPase; Small GTPase of the Ras superfamily; ill-defined subfamily
    cl21455
    Location:11 → 172
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    111451043..111452257 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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