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Zfp729a zinc finger protein 729a [ Mus musculus (house mouse) ]

Gene ID: 212281, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp729aprovided by MGI
Official Full Name
zinc finger protein 729aprovided by MGI
Primary source
MGI:MGI:3036250
See related
Ensembl:ENSMUSG00000021510 AllianceGenome:MGI:3036250
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rslcan3; A530054K11Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated; negative regulation of transposon integration; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF91 (zinc finger protein 91). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 1.6), CNS E18 (RPKM 1.4) and 25 other tissues See more
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Genomic context

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Location:
13 B3; 13 34.62 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67760879..67785925, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (67612760..67637803, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9430065F17 gene Neighboring gene STARR-positive B cell enhancer ABC_E9881 Neighboring gene zinc finger protein 729b Neighboring gene STARR-positive B cell enhancer ABC_E4077 Neighboring gene STARR-seq mESC enhancer starr_34905 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:67738709-67738896 Neighboring gene predicted gene, 46439 Neighboring gene STARR-seq mESC enhancer starr_34906 Neighboring gene zinc finger protein 738

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrotransposon silencing ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC212281
Names
regulator of sex-limitation candidate 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001401864.1 → NP_001388793.1  uncharacterized protein LOC212281 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT571249, CT573016

  2. NM_001401865.1 → NP_001388794.1  uncharacterized protein LOC212281 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT571249, CT573016

  3. NM_001401866.1 → NP_001388795.1  uncharacterized protein LOC212281 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT571249, CT573016

  4. NM_183146.5 → NP_898969.2  uncharacterized protein LOC212281 isoform 1

    See identical proteins and their annotated locations for NP_898969.2

    Status: VALIDATED

    Source sequence(s)
    CT571249, CT573016
    Consensus CDS
    CCDS26617.1
    UniProtKB/TrEMBL
    Q4QQP3
    Related
    ENSMUSP00000012314.8, ENSMUST00000012314.10
    Conserved Domains (5) summary
    smart00349
    Location:15 → 73
    KRAB; krueppel associated box
    COG5048
    Location:229 → 670
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:485 → 505
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:15 → 54
    KRAB; KRAB box
    pfam13465
    Location:497 → 522
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    67760879..67785925 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157962.1 → XP_036013855.1  uncharacterized protein LOC212281 isoform X2

    Conserved Domains (3) summary
    smart00349
    Location:15 → 73
    KRAB; krueppel associated box
    COG5048
    Location:116 → 503
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:233 → 253
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_011244504.4 → XP_011242806.1  uncharacterized protein LOC212281 isoform X1

    See identical proteins and their annotated locations for XP_011242806.1

    Conserved Domains (4) summary
    smart00349
    Location:2 → 60
    KRAB; krueppel associated box
    COG5048
    Location:216 → 657
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:130 → 199
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:472 → 492
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_036157961.1 → XP_036013854.1  uncharacterized protein LOC212281 isoform X1

    Conserved Domains (4) summary
    smart00349
    Location:2 → 60
    KRAB; krueppel associated box
    COG5048
    Location:216 → 657
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:130 → 199
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:472 → 492
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_873435.4 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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