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Ubxn10 UBX domain protein 10 [ Mus musculus (house mouse) ]

Gene ID: 212190, updated on 5-Mar-2024

Summary

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Official Symbol
Ubxn10provided by MGI
Official Full Name
UBX domain protein 10provided by MGI
Primary source
MGI:MGI:2443123
See related
Ensembl:ENSMUSG00000043621 AllianceGenome:MGI:2443123
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ubxd3; A830047D02; 5730509E04Rik
Summary
Predicted to be involved in cilium assembly. Predicted to act upstream of or within cell projection organization. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle B. Is expressed in sensory organ and skeleton. Orthologous to human UBXN10 (UBX domain protein 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 108.6), ovary adult (RPKM 10.0) and 1 other tissue See more
Orthologs
human all
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Genomic context

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Location:
4 D3; 4 70.53 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (138437148..138465749, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (138709837..138738438, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_11810 Neighboring gene von Willebrand factor A domain containing 5B1 Neighboring gene predicted gene, 32662 Neighboring gene predicted gene, 32770 Neighboring gene STARR-seq mESC enhancer starr_11814 Neighboring gene phospholipase A2, group IIC Neighboring gene predicted gene, 57720 Neighboring gene phospholipase A2, group IIF Neighboring gene predicted gene, 42332

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
  
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cilium ISO
Inferred from Sequence Orthology
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of intraciliary transport particle B ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
UBX domain-containing protein 10
Names
UBX domain containing 3
UBX domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001285928.1 → NP_001272857.1  UBX domain-containing protein 10

    See identical proteins and their annotated locations for NP_001272857.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AK046949, AK161245
    Consensus CDS
    CCDS18830.1
    UniProtKB/Swiss-Prot
    Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
    UniProtKB/TrEMBL
    Q3TTM2
    Related
    ENSMUSP00000101436.2, ENSMUST00000105810.8
    Conserved Domains (1) summary
    cl00155
    Location:190 → 266
    UBQ; Ubiquitin-like proteins

  2. NM_001285929.1 → NP_001272858.1  UBX domain-containing protein 10

    See identical proteins and their annotated locations for NP_001272858.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AK161245, AL844178
    Consensus CDS
    CCDS18830.1
    UniProtKB/Swiss-Prot
    Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
    UniProtKB/TrEMBL
    Q3TTM2
    Conserved Domains (1) summary
    cl00155
    Location:190 → 266
    UBQ; Ubiquitin-like proteins

  3. NM_001285930.1 → NP_001272859.1  UBX domain-containing protein 10

    See identical proteins and their annotated locations for NP_001272859.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AK161245, AL844178
    Consensus CDS
    CCDS18830.1
    UniProtKB/Swiss-Prot
    Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
    UniProtKB/TrEMBL
    Q3TTM2
    Related
    ENSMUSP00000101435.2, ENSMUST00000105809.2
    Conserved Domains (1) summary
    cl00155
    Location:190 → 266
    UBQ; Ubiquitin-like proteins

  4. NM_178671.5 → NP_848786.1  UBX domain-containing protein 10

    See identical proteins and their annotated locations for NP_848786.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 all encode the same protein.
    Source sequence(s)
    AK077656, AK161245
    Consensus CDS
    CCDS18830.1
    UniProtKB/Swiss-Prot
    Q3TTR1, Q8BG34, Q8BP58, Q8R0B6
    UniProtKB/TrEMBL
    Q3TTM2
    Related
    ENSMUSP00000101437.3, ENSMUST00000105811.9
    Conserved Domains (1) summary
    cl00155
    Location:190 → 266
    UBQ; Ubiquitin-like proteins

RNA

  1. NR_104373.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) contains alternate 3' exon structure compared to variant 1. This variant is represented as non-coding because use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK045964, AK077656, AW494942

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    138437148..138465749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BG34.1 GenPept UniProtKB/Swiss-Prot:Q8BG34

Gene LinkOut

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