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Tmem87a transmembrane protein 87A [ Mus musculus (house mouse) ]

Gene ID: 211499, updated on 2-Apr-2024

Summary

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Official Symbol
Tmem87aprovided by MGI
Official Full Name
transmembrane protein 87Aprovided by MGI
Primary source
MGI:MGI:2441844
See related
Ensembl:ENSMUSG00000033808 AllianceGenome:MGI:2441844
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A930025J12Rik
Summary
Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be integral component of membrane. Predicted to be active in Golgi cisterna membrane. Is expressed in facial ganglion. Orthologous to human TMEM87A (transmembrane protein 87A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 9.4), bladder adult (RPKM 9.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
2 E5; 2 60.31 cM
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120185790..120234597, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (120355309..120404154, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phospholipase A2, group IVF Neighboring gene VPS39 HOPS complex subunit Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:120178706-120178815 Neighboring gene STARR-positive B cell enhancer ABC_E10133 Neighboring gene STARR-positive B cell enhancer ABC_E9071 Neighboring gene glucosidase, alpha; neutral C Neighboring gene RIKEN cDNA 4931402G19 gene Neighboring gene STARR-seq mESC enhancer starr_05508 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:120308865-120309066 Neighboring gene calpain 3 Neighboring gene STARR-seq mESC enhancer starr_05509 Neighboring gene zinc finger protein 106 Neighboring gene STARR-seq mESC enhancer starr_05510

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. BDNF and NT4 play interchangeable roles in gustatory development. Huang T, et al. Dev Biol, 2014 Feb 15. PMID 24378336, Free PMC Article
  2. Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain. Lee Y, et al. Biochem Biophys Res Commun, 2020 Aug 13. PMID 32560809
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
  5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Touch sensation requires the mechanically gated ion channel ELKIN1.
    Title: Touch sensation requires the mechanically gated ion channel ELKIN1.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cellular response to mechanical stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde transport, endosome to Golgi ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
is_active_in Golgi cisterna membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi cisterna membrane ISO
Inferred from Sequence Orthology
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in ruffle ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
transmembrane protein 87A
Names
elkin1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110496.1 → NP_001103966.1  transmembrane protein 87A isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AK044591, AL844608, BY149198
    Consensus CDS
    CCDS50677.1
    UniProtKB/Swiss-Prot
    Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
    UniProtKB/TrEMBL
    A2AQJ5
    Related
    ENSMUSP00000087496.6, ENSMUST00000090042.12
    Conserved Domains (1) summary
    pfam06814
    Location:210 → 471
    Lung_7-TM_R; Lung seven transmembrane receptor

  2. NM_001110497.1 → NP_001103967.1  transmembrane protein 87A isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AK086738, AL844608, BY149198
    UniProtKB/Swiss-Prot
    Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
    Conserved Domains (1) summary
    pfam06814
    Location:210 → 471
    Lung_7-TM_R; Lung seven transmembrane receptor

  3. NM_173734.3 → NP_776095.2  transmembrane protein 87A isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AK044591, AK134268, AL844608, BY149198
    Consensus CDS
    CCDS50678.1
    UniProtKB/Swiss-Prot
    Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
    UniProtKB/TrEMBL
    A2AQJ6
    Related
    ENSMUSP00000087500.6, ENSMUST00000090046.12
    Conserved Domains (1) summary
    pfam06814
    Location:210 → 472
    Lung_7-TM_R; Lung seven transmembrane receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    120185790..120234597 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499077.3 → XP_006499140.1  transmembrane protein 87A isoform X1

    UniProtKB/Swiss-Prot
    Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
    Related
    ENSMUST00000136410.8
    Conserved Domains (1) summary
    pfam06814
    Location:186 → 472
    Lung_7-TM_R; Lung seven transmembrane receptor

  2. XM_011239411.2 → XP_011237713.1  transmembrane protein 87A isoform X4

    Conserved Domains (1) summary
    pfam06814
    Location:43 → 329
    Lung_7-TM_R; Lung seven transmembrane receptor

  3. XM_011239409.1 → XP_011237711.1  transmembrane protein 87A isoform X2

    UniProtKB/Swiss-Prot
    Q8BTV9, Q8BU98, Q8BXN9, Q8R2P9, Q8R3S7
    Conserved Domains (1) summary
    pfam06814
    Location:138 → 424
    Lung_7-TM_R; Lung seven transmembrane receptor

  4. XM_011239410.3 → XP_011237712.1  transmembrane protein 87A isoform X3

    UniProtKB/TrEMBL
    A2AQJ7
    Related
    ENSMUSP00000106357.2, ENSMUST00000110729.2
    Conserved Domains (1) summary
    pfam06814
    Location:186 → 472
    Lung_7-TM_R; Lung seven transmembrane receptor

  5. XM_011239412.4 → XP_011237714.1  transmembrane protein 87A isoform X5

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BXN9.1 GenPept UniProtKB/Swiss-Prot:Q8BXN9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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