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Mcmbp minichromosome maintenance complex binding protein [ Mus musculus (house mouse) ]

Gene ID: 210711, updated on 5-Mar-2024

Summary

Official Symbol
Mcmbpprovided by MGI
Official Full Name
minichromosome maintenance complex binding proteinprovided by MGI
Primary source
MGI:MGI:1920977
See related
Ensembl:ENSMUSG00000048170 AllianceGenome:MGI:1920977
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MCM-BP; 1110007A13Rik
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in DNA-dependent DNA replication and sister chromatid cohesion. Predicted to act upstream of or within DNA replication and cell division. Predicted to be located in cell junction; cytosol; and nucleoplasm. Predicted to be part of MCM complex. Orthologous to human MCMBP (minichromosome maintenance complex binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 21.9), thymus adult (RPKM 17.2) and 28 other tissues See more
Orthologs
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Genomic context

Location:
7 F3; 7 70.41 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (128298165..128342153, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (128696441..128740429, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1743 Neighboring gene mitochondrial ribosomal protein S36 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3756 Neighboring gene inositol polyphosphate-5-phosphatase F Neighboring gene pentatricopeptide repeat domain 3 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3757 Neighboring gene Sec23 interacting protein Neighboring gene STARR-seq mESC enhancer starr_20212 Neighboring gene STARR-seq mESC enhancer starr_20213 Neighboring gene STARR-seq mESC enhancer starr_20214 Neighboring gene predicted gene, 39093

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC36596

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables chromatin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA-templated DNA replication ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in sister chromatid cohesion ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of MCM complex ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mini-chromosome maintenance complex-binding protein
Names
MCM (minichromosome maintenance deficient) binding protein
MCM-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145955.3NP_666067.1  mini-chromosome maintenance complex-binding protein

    See identical proteins and their annotated locations for NP_666067.1

    Status: PROVISIONAL

    Source sequence(s)
    AC122767, AC136741
    Consensus CDS
    CCDS40153.1
    UniProtKB/Swiss-Prot
    D3Z3G1, Q8R3C0
    UniProtKB/TrEMBL
    H9KV04
    Related
    ENSMUSP00000062843.8, ENSMUST00000057557.14
    Conserved Domains (1) summary
    pfam09739
    Location:36628
    MCM_bind; Mini-chromosome maintenance replisome factor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    128298165..128342153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)