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Zfp719 zinc finger protein 719 [ Mus musculus (house mouse) ]

Gene ID: 210105, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp719provided by MGI
Official Full Name
zinc finger protein 719provided by MGI
Primary source
MGI:MGI:2444708
See related
Ensembl:ENSMUSG00000030469 AllianceGenome:MGI:2444708
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mszf6; 8030458J18; 9430094P17Rik; C630016O21Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 2.3), cerebellum adult (RPKM 2.2) and 26 other tissues See more
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Genomic context

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Location:
7 B3; 7 28.25 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43228988..43243134)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43579559..43593710)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CD33 molecule Neighboring gene zinc finger protein 658 Neighboring gene STARR-positive B cell enhancer ABC_E9290 Neighboring gene STARR-seq mESC enhancer starr_18778 Neighboring gene STARR-seq mESC enhancer starr_18779 Neighboring gene zinc finger protein 819 Neighboring gene CEA cell adhesion molecule 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A gene expression resource generated by genome-wide lacZ profiling in the mouse. Tuck E, et al. Dis Model Mech, 2015 Nov. PMID 26398943, Free PMC Article
  2. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
  3. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
  4. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 719

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357769.1 → NP_001344698.1  zinc finger protein 719

    Status: VALIDATED

    Source sequence(s)
    AC154108
    Consensus CDS
    CCDS52225.1
    UniProtKB/TrEMBL
    Q8BIV1
    Conserved Domains (3) summary
    COG5048
    Location:335 → 708
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:567 → 587
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:48 → 89
    KRAB; KRAB box

  2. NM_172482.1 → NP_766070.1  zinc finger protein 719

    See identical proteins and their annotated locations for NP_766070.1

    Status: VALIDATED

    Source sequence(s)
    AC154108, AK044684, AK083143, BB684430, CJ086175
    Consensus CDS
    CCDS52225.1
    UniProtKB/TrEMBL
    Q8BIV1
    Related
    ENSMUSP00000050968.8, ENSMUST00000058104.8
    Conserved Domains (3) summary
    COG5048
    Location:335 → 708
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:567 → 587
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:48 → 89
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    43228988..43243134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152866.1 → XP_036008759.1  zinc finger protein 719 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:295 → 668
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:527 → 547
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:8 → 49
    KRAB; KRAB box

  2. XM_011250841.4 → XP_011249143.1  zinc finger protein 719 isoform X3

    See identical proteins and their annotated locations for XP_011249143.1

    Conserved Domains (2) summary
    COG5048
    Location:258 → 631
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:490 → 510
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_036152865.1 → XP_036008758.1  zinc finger protein 719 isoform X1

    UniProtKB/TrEMBL
    Q8BIV1
    Conserved Domains (3) summary
    COG5048
    Location:335 → 708
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:567 → 587
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:48 → 89
    KRAB; KRAB box
Nucleotide Protein Strain
Heading Accession and Version

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