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Slc35f3 solute carrier family 35, member F3 [ Mus musculus (house mouse) ]

Gene ID: 210027, updated on 5-Mar-2024

Summary

Official Symbol
Slc35f3provided by MGI
Official Full Name
solute carrier family 35, member F3provided by MGI
Primary source
MGI:MGI:2444426
See related
Ensembl:ENSMUSG00000057060 AllianceGenome:MGI:2444426
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B230375D17Rik
Summary
Predicted to be involved in thiamine transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SLC35F3 (solute carrier family 35 member F3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 19.1), ovary adult (RPKM 16.7) and 28 other tissues See more
Orthologs
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Genomic context

Location:
8 E2; 8 73.82 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (126865155..127122726)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (126138398..126395987)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene potassium channel, subfamily K, member 1 Neighboring gene STARR-seq mESC enhancer starr_23054 Neighboring gene STARR-seq mESC enhancer starr_23055 Neighboring gene predicted gene, 53470 Neighboring gene predicted gene, 46072 Neighboring gene predicted gene, 31165 Neighboring gene STARR-seq mESC enhancer starr_23057 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_23059 Neighboring gene STARR-positive B cell enhancer ABC_E8274 Neighboring gene predicted gene, 51604 Neighboring gene predicted gene, 51604 Neighboring gene TAR RNA binding protein 1 Neighboring gene cytochrome c oxidase assembly factor 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Clone Names

  • MGC141263, MGC141264

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in thiamine transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in thiamine transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier family 35 member F3
Names
putative thiamine transporter SLC35F3
thiamine transporter SLC35F3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363500.1NP_001350429.1  solute carrier family 35 member F3 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC122236, AC125192
    UniProtKB/TrEMBL
    A0A571BEK8
    Related
    ENSMUSP00000158727.2, ENSMUST00000238518.2
    Conserved Domains (2) summary
    pfam06027
    Location:215388
    SLC35F; Solute carrier family 35
    pfam00892
    Location:118273
    EamA; EamA-like transporter family
  2. NM_175434.3NP_780643.2  solute carrier family 35 member F3 isoform 2

    See identical proteins and their annotated locations for NP_780643.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    AC122236, BB318499, BC115965, CJ057689
    Consensus CDS
    CCDS40520.1
    UniProtKB/Swiss-Prot
    Q1LZI2, Q8BL51
    UniProtKB/TrEMBL
    A0A571BEK8
    Related
    ENSMUSP00000104390.3, ENSMUST00000108759.3
    Conserved Domains (1) summary
    pfam00892
    Location:67223
    EamA; EamA-like transporter family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    126865155..127122726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248334.3XP_011246636.1  solute carrier family 35 member F3 isoform X1

    UniProtKB/TrEMBL
    A0A571BEK8
    Conserved Domains (2) summary
    pfam06027
    Location:215388
    SLC35F; Solute carrier family 35
    pfam00892
    Location:118273
    EamA; EamA-like transporter family
  2. XM_030243383.2XP_030099243.1  solute carrier family 35 member F3 isoform X5

  3. XM_030243382.1XP_030099242.1  solute carrier family 35 member F3 isoform X3

    Conserved Domains (1) summary
    cl28899
    Location:849
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
  4. XM_011248335.3XP_011246637.1  solute carrier family 35 member F3 isoform X4

    Conserved Domains (1) summary
    cl28899
    Location:849
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
  5. XM_030243381.2XP_030099241.1  solute carrier family 35 member F3 isoform X2

    UniProtKB/TrEMBL
    A0A571BFY6
    Conserved Domains (1) summary
    pfam06027
    Location:73182
    SLC35F; Solute carrier family 35
  6. XM_006530806.4XP_006530869.1  solute carrier family 35 member F3 isoform X2

    See identical proteins and their annotated locations for XP_006530869.1

    UniProtKB/TrEMBL
    A0A571BFY6
    Conserved Domains (1) summary
    pfam06027
    Location:73182
    SLC35F; Solute carrier family 35