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Tmem132b transmembrane protein 132B [ Mus musculus (house mouse) ]

Gene ID: 208151, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem132bprovided by MGI
Official Full Name
transmembrane protein 132Bprovided by MGI
Primary source
MGI:MGI:3609245
See related
Ensembl:ENSMUSG00000070498 AllianceGenome:MGI:3609245
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1786
Summary
Orthologous to human TMEM132B (transmembrane protein 132B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cortex adult (RPKM 8.4), frontal lobe adult (RPKM 6.6) and 5 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 G1.1; 5 64.27 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (125609449..125869647)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (125532418..125792583)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E853 Neighboring gene STARR-positive B cell enhancer ABC_E6383 Neighboring gene STARR-positive B cell enhancer ABC_E6384 Neighboring gene predicted gene, 40325 Neighboring gene acetoacetyl-CoA synthetase Neighboring gene STARR-seq mESC enhancer starr_14382 Neighboring gene predicted gene, 32811 Neighboring gene microRNA 12200 Neighboring gene predicted gene, 40327 Neighboring gene predicted gene 4868

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Differential expression of the Tmem132 family genes in the developing mouse nervous system. Wang Y, et al. Gene Expr Patterns, 2022 Sep. PMID 35690356, Free PMC Article
  2. Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome. Li J, et al. Sci Signal, 2016 Aug 9. PMID 27507650
  3. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA1786

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
transmembrane protein 132B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190352.2 → NP_001177281.1  transmembrane protein 132B precursor

    Status: VALIDATED

    Source sequence(s)
    AC100382, AC119268
    Consensus CDS
    CCDS57384.1
    UniProtKB/TrEMBL
    F7BAB2
    Related
    ENSMUSP00000031446.6, ENSMUST00000031446.7
    Conserved Domains (3) summary
    pfam15705
    Location:45 → 173
    TMEM132D_N; Mature oligodendrocyte transmembrane protein, TMEM132D, N-term
    pfam15706
    Location:870 → 953
    TMEM132D_C; Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
    pfam16070
    Location:432 → 773
    TMEM132; Transmembrane protein family 132

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    125609449..125869647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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