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Mucl2 mucin-like 2 [ Mus musculus (house mouse) ]

Gene ID: 20770, updated on 8-Feb-2024

Summary

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Official Symbol
Mucl2provided by MGI
Official Full Name
mucin-like 2provided by MGI
Primary source
MGI:MGI:98392
See related
Ensembl:ENSMUSG00000036925 AllianceGenome:MGI:98392
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Spt1; Spt-1
Summary
Predicted to be located in extracellular region. Is expressed in thymus and thymus primordium. Orthologous to human MUCL1 (mucin like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Mucl2 in Genome Data Viewer
Location:
15 F3; 15
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (103926121..103929578, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (103895855..103899312, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene mucin-like 1 Neighboring gene predicted gene, 21178

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A new member of the hormonally regulated rodent submaxillary gland glycoprotein gene family: cDNA cloning and tissue specific expression. Myal Y, et al. Mol Cell Endocrinol, 1996 Jul 1. PMID 8832572
  2. Molecular cloning of cDNAs from androgen-independent mRNA species of DBA/2 mouse sub-maxillary glands. Windass JD, et al. Nucleic Acids Res, 1984 Feb 10. PMID 6546617, Free PMC Article
  3. Rapid evolution of variants in a rodent multigene family encoding salivary proteins. Dickinson DP, et al. Mol Biol Evol, 1989 Jan. PMID 2921944
  4. Genetic and tissue-specific variation in the expression of a closely linked murine multigene family on chromosome 15 that encodes salivary and lacrimal proteins. Dickinson DP, et al. Biochem Genet, 1989 Oct. PMID 2482730
  5. Modulation of Aire regulates the expression of tissue-restricted antigens. Kont V, et al. Mol Immunol, 2008 Jan. PMID 17599412, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC29130, MGC118102

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mucin-like protein 2
Names
16.5 kDa submandibular gland glycoprotein
salivary protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009267.2 → NP_033293.2  mucin-like protein 2 precursor

    See identical proteins and their annotated locations for NP_033293.2

    Status: VALIDATED

    Source sequence(s)
    CK616337, CK616968
    Consensus CDS
    CCDS57015.1
    UniProtKB/Swiss-Prot
    P02815, Q3KQK8, Q62263, Q9DA65
    Related
    ENSMUSP00000044814.7, ENSMUST00000037685.9
    Conserved Domains (1) summary
    COG4547
    Location:20 → 137
    CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    103926121..103929578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159293.1 → XP_036015186.1  mucin-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A2I3BRY2
    Related
    ENSMUSP00000154772.2, ENSMUST00000226584.2
    Conserved Domains (1) summary
    PRK08581
    Location:9 → 128
    PRK08581; amidase domain-containing protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02815.2 GenPept UniProtKB/Swiss-Prot:P02815

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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