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Fam120c family with sequence similarity 120, member C [ Mus musculus (house mouse) ]

Gene ID: 207375, updated on 5-Mar-2024

Summary

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Official Symbol
Fam120cprovided by MGI
Official Full Name
family with sequence similarity 120, member Cprovided by MGI
Primary source
MGI:MGI:2387687
See related
Ensembl:ENSMUSG00000025262 AllianceGenome:MGI:2387687
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ORF34; D930001I21Rik
Summary
Predicted to be active in nucleus. Is expressed in brain; embryo; skeletal muscle; and testis. Orthologous to human FAM120C (family with sequence similarity 120C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in frontal lobe adult (RPKM 4.9), cerebellum adult (RPKM 4.3) and 27 other tissues See more
Orthologs
human all
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Genomic context

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Location:
X F3; X 68.46 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (150125515..150257135)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (151342519..151474139)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene WNK lysine deficient protein kinase 3 Neighboring gene predicted gene, 26441 Neighboring gene RIKEN cDNA A230072E10 gene Neighboring gene STARR-positive B cell enhancer mm9_chrX:147778291-147778592 Neighboring gene importin 5 pseudogene Neighboring gene predicted gene, 22248 Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene STARR-seq mESC enhancer starr_48081 Neighboring gene ribosomal protein L39 pseudogene Neighboring gene predicted gene, 24460 Neighboring gene PHD finger protein 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in mice. Baker AB, et al. Circ Res, 2009 Feb 13. PMID 19096032, Free PMC Article
  2. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. Holden S, et al. Gene, 2003 Oct 30. PMID 14585507
  3. Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant. Quinlan MA, et al. Front Mol Neurosci, 2020. PMID 32581705, Free PMC Article
  4. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. Das R, et al. J Cell Sci, 2019 Jun 17. PMID 31138677, Free PMC Article
  5. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
constitutive coactivator of PPAR-gamma-like protein 2
Names
family with sequence similarity 120C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198105.2 → NP_932773.2  constitutive coactivator of PPAR-gamma-like protein 2

    See identical proteins and their annotated locations for NP_932773.2

    Status: VALIDATED

    Source sequence(s)
    AK030477, AK136727, AL662922
    Consensus CDS
    CCDS41175.1
    UniProtKB/Swiss-Prot
    Q3U0F6, Q8C3F2
    UniProtKB/TrEMBL
    B7ZW94
    Related
    ENSMUSP00000073082.6, ENSMUST00000073364.6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    150125515..150257135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247802.4 → XP_011246104.1  constitutive coactivator of PPAR-gamma-like protein 2 isoform X1

    Conserved Domains (2) summary
    pfam08549
    Location:426 → 460
    SWI-SNF_Ssr4; Fungal domain of unknown function (DUF1750)
    cl28905
    Location:5 → 276
    PIN_SF; PIN (PilT N terminus) domain: Superfamily

  2. XM_030251275.2 → XP_030107135.1  constitutive coactivator of PPAR-gamma-like protein 2 isoform X2

RNA

  1. XR_004940330.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C3F2.3 GenPept UniProtKB/Swiss-Prot:Q8C3F2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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