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Saa4 serum amyloid A 4 [ Mus musculus (house mouse) ]

Gene ID: 20211, updated on 5-Mar-2024

Summary

Official Symbol
Saa4provided by MGI
Official Full Name
serum amyloid A 4provided by MGI
Primary source
MGI:MGI:98224
See related
Ensembl:ENSMUSG00000040017 AllianceGenome:MGI:98224
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Saa-4; Saa-5
Summary
Predicted to act upstream of or within acute-phase response. Predicted to be located in extracellular region. Predicted to be part of high-density lipoprotein particle. Orthologous to several human genes including SAA4 (serum amyloid A4, constitutive). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver adult (RPKM 29.6), liver E18 (RPKM 9.3) and 3 other tissues See more
Orthologs
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Genomic context

Location:
7 B3; 7 30.53 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (46377416..46382027, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (46727992..46732603, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene serum amyloid A 3 Neighboring gene predicted gene, 31882 Neighboring gene serum amyloid A, pseudogene Neighboring gene serum amyloid A 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General protein information

Preferred Names
serum amyloid A-4 protein
Names
amyloid A-5 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011316.4NP_035446.1  serum amyloid A-4 protein precursor

    See identical proteins and their annotated locations for NP_035446.1

    Status: VALIDATED

    Source sequence(s)
    AC090122, CJ134068
    Consensus CDS
    CCDS21283.1
    UniProtKB/Swiss-Prot
    P31532
    Related
    ENSMUSP00000006952.8, ENSMUST00000006952.9
    Conserved Domains (1) summary
    smart00197
    Location:21130
    SAA; Serum amyloid A proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    46377416..46382027 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)