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Rps18 ribosomal protein S18 [ Mus musculus (house mouse) ]

Gene ID: 20084, updated on 5-Mar-2024

Summary

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Official Symbol
Rps18provided by MGI
Official Full Name
ribosomal protein S18provided by MGI
Primary source
MGI:MGI:98146
See related
Ensembl:ENSMUSG00000008668 AllianceGenome:MGI:98146
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ke3; Ke-3; H-2Ke3; H2-Ke3
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Is active in synapse. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and liver. Orthologous to human RPS18 (ribosomal protein S18). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 498.9), liver E18 (RPKM 438.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17 B1; 17 17.98 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (34170972..34174639, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (33951998..33955665, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1938 Neighboring gene WD repeat domain 46 Neighboring gene STARR-positive B cell enhancer ABC_E8668 Neighboring gene UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 Neighboring gene STARR-positive B cell enhancer ABC_E3199 Neighboring gene VPS52 GARP complex subunit Neighboring gene predicted gene, 23111 Neighboring gene STARR-positive B cell enhancer ABC_E2483 Neighboring gene histocompatibility 2, K region locus 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Search for MHC-associated genes in human: five new genes centromeric to HLA-DP with yet unknown functions. Janatipour M, et al. Immunogenetics, 1992. PMID 1541487
  2. Expression of a gene trap reporter construct in a subset of cells in embryonic sites of hematopoiesis: evidence for alternative rRNA production in hematopoietic cells. Wagner DS, et al. Biochem Biophys Res Commun, 1998 Sep 29. PMID 9784405
  3. Processing of mammalian rRNA precursors at the 3' end of 18S rRNA. Identification of cis-acting signals suggests the involvement of U13 small nucleolar RNA. Cavaillé J, et al. Eur J Biochem, 1996 Dec 1. PMID 8973634
  4. Impaired bone formation in Pdia3 deficient mice. Wang Y, et al. PLoS One, 2014. PMID 25405762, Free PMC Article
  5. The murine MHC encodes a mammalian homolog of bacterial ribosomal protein S13. MacMurray AJ, et al. Mamm Genome, 1992. PMID 1543907

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
part_of small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
small ribosomal subunit protein uS13
Names
40S ribosomal protein S18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011296.3 → NP_035426.1  small ribosomal subunit protein uS13

    See identical proteins and their annotated locations for NP_035426.1

    Status: VALIDATED

    Source sequence(s)
    CR974462
    Consensus CDS
    CCDS37573.1
    UniProtKB/Swiss-Prot
    P62270
    UniProtKB/TrEMBL
    Q3TW65, Q561N5
    Related
    ENSMUSP00000008812.8, ENSMUST00000008812.9
    Conserved Domains (1) summary
    PTZ00134
    Location:1 → 152
    PTZ00134; 40S ribosomal protein S18; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    34170972..34174639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_138946.1: Suppressed sequence

    Description
    NM_138946.1: This RefSeq was permanently suppressed because it was entirely composed of intronic sequence.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62270.3 GenPept UniProtKB/Swiss-Prot:P62270

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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