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Rpl30 ribosomal protein L30 [ Mus musculus (house mouse) ]

Gene ID: 19946, updated on 11-Apr-2024

Summary

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Official Symbol
Rpl30provided by MGI
Official Full Name
ribosomal protein L30provided by MGI
Primary source
MGI:MGI:98037
See related
Ensembl:ENSMUSG00000058600 AllianceGenome:MGI:98037
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable selenocysteine insertion sequence binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; cytoplasmic translation; and defense response to Gram-negative bacterium. Is active in postsynaptic density. Is expressed in brain. Human ortholog(s) of this gene implicated in herpes simplex. Orthologous to human RPL30 (ribosomal protein L30). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 355.7), liver E14 (RPKM 337.8) and 24 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 B3.1; 15 14.33 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (34440649..34443405, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (34440505..34443276, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene lysosomal-associated protein transmembrane 4B Neighboring gene eukaryotic translation initiation factor 4A2 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:34225853-34226040 Neighboring gene matrilin 2 Neighboring gene RIKEN cDNA 9430069I07 gene Neighboring gene STARR-seq mESC enhancer starr_38326 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:34372917-34373070 Neighboring gene predicted gene, 24523 Neighboring gene glutamate rich 5 Neighboring gene reactive intermediate imine deaminase A homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Three functional ribosomal protein genes are unlinked in mouse genome. Wiedemann LM, et al. Somat Cell Mol Genet, 1987 Jan. PMID 3468635
  2. Characterization of the expressed gene and several processed pseudogenes for the mouse ribosomal protein L30 gene family. Wiedemann LM, et al. Mol Cell Biol, 1984 Nov. PMID 6513928, Free PMC Article
  3. Chromosomal distribution of ribosomal protein genes in the mouse. D'Eustachio P, et al. Cell, 1981 May. PMID 7237550
  4. The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome. Feo S, et al. Genomics, 1992 May. PMID 1577483
  5. The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression. Nakagawa T, et al. iScience, 2020 Apr 24. PMID 32299058, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC106425, MGC107559

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables selenocysteine insertion sequence binding ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoplasmic translation ISO
Inferred from Sequence Orthology
more info
  
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in defense response to Gram-negative bacterium ISO
Inferred from Sequence Orthology
more info
  
involved_in killing of cells of another organism ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
is_active_in postsynapse NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in postsynaptic density EXP
Inferred from Experiment
more info
 PubMed 
is_active_in postsynaptic density IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
 PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
large ribosomal subunit protein eL30
Names
60S ribosomal protein L30

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163485.2 → NP_001156957.1  large ribosomal subunit protein eL30

    See identical proteins and their annotated locations for NP_001156957.1

    Status: VALIDATED

    Source sequence(s)
    AC126028
    Consensus CDS
    CCDS37057.1
    UniProtKB/Swiss-Prot
    P62889
    UniProtKB/TrEMBL
    Q497D7, Q58DZ3, Q5PR15
    Related
    ENSMUSP00000106014.2, ENSMUST00000079735.12
    Conserved Domains (1) summary
    PTZ00106
    Location:2 → 107
    PTZ00106; 60S ribosomal protein L30; Provisional

  2. NM_009083.5 → NP_033109.1  large ribosomal subunit protein eL30

    See identical proteins and their annotated locations for NP_033109.1

    Status: VALIDATED

    Source sequence(s)
    AC126028
    Consensus CDS
    CCDS37057.1
    UniProtKB/Swiss-Prot
    P62889
    UniProtKB/TrEMBL
    Q497D7, Q58DZ3, Q5PR15
    Related
    ENSMUSP00000009039.6, ENSMUST00000009039.6
    Conserved Domains (1) summary
    PTZ00106
    Location:2 → 107
    PTZ00106; 60S ribosomal protein L30; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    34440649..34443405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_001450.1: Suppressed sequence

    Description
    NG_001450.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P62889.2 GenPept UniProtKB/Swiss-Prot:P62889

Gene LinkOut

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