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Serpina16 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16 [ Mus musculus (house mouse) ]

Gene ID: 194604, updated on 8-Feb-2024

Summary

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Official Symbol
Serpina16provided by MGI
Official Full Name
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16provided by MGI
Primary source
MGI:MGI:2684892
See related
Ensembl:ENSMUSG00000071179 AllianceGenome:MGI:2684892
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm46
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 224.2) See more
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Genomic context

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Location:
12 E; 12 52.98 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (103635067..103643100, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (103668808..103676841, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene crumbs homolog 1 pseudogene Neighboring gene serine (or cysteine) peptidase inhibitor, clade A, member 6 Neighboring gene predicted gene, 46373 Neighboring gene serine (or cysteine) peptidase inhibitor, clade A, member 1F Neighboring gene serine (or cysteine) preptidase inhibitor, clade A, member 1B pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310472.1 → NP_001297401.1  serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16 precursor

    See identical proteins and their annotated locations for NP_001297401.1

    Status: VALIDATED

    Source sequence(s)
    AC098741, AC125360
    Consensus CDS
    CCDS79151.1
    UniProtKB/TrEMBL
    D3Z660
    Conserved Domains (1) summary
    cl38926
    Location:39 → 409
    serpin; SERine Proteinase INhibitors (serpin) family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    103635067..103643100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_112098.8 → XP_112098.3  serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16 isoform X1

    Conserved Domains (1) summary
    cl38926
    Location:61 → 431
    serpin; SERine Proteinase INhibitors (serpin) family

  2. XM_006516443.2 → XP_006516506.1  serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16 isoform X2

    See identical proteins and their annotated locations for XP_006516506.1

    UniProtKB/TrEMBL
    D3Z660
    Related
    ENSMUSP00000126933.2, ENSMUST00000164148.8
    Conserved Domains (1) summary
    cl38926
    Location:39 → 409
    serpin; SERine Proteinase INhibitors (serpin) family
Nucleotide Protein
Heading Accession and Version

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