U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rab24 RAB24, member RAS oncogene family [ Mus musculus (house mouse) ]

Gene ID: 19336, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Rab24provided by MGI
Official Full Name
RAB24, member RAS oncogene familyprovided by MGI
Primary source
MGI:MGI:105065
See related
Ensembl:ENSMUSG00000034789 AllianceGenome:MGI:105065
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6530406O07Rik
Summary
Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to act upstream of or within autophagy and protein transport. Located in autophagosome. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Orthologous to human RAB24 (RAB24, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 32.6), CNS E11.5 (RPKM 31.7) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rab24 in Genome Data Viewer
Location:
13 B1; 13 29.8 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (55467036..55469807, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (55319223..55321980, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor receptor 4 Neighboring gene STARR-positive B cell enhancer ABC_E5399 Neighboring gene STARR-seq mESC enhancer starr_34607 Neighboring gene nuclear receptor-binding SET-domain protein 1 Neighboring gene STARR-seq mESC enhancer starr_34609 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:55429152-55429261 Neighboring gene PRELI domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_34614 Neighboring gene Max dimerization protein 3 Neighboring gene STARR-positive B cell enhancer ABC_E7242 Neighboring gene lectin, mannose-binding 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Rab24 functions in meiotic apparatus assembly and maturational progression in mouse oocyte. Qiu D, et al. Cell Cycle, 2019 Nov. PMID 31496367, Free PMC Article
  2. RAB24 facilitates clearance of autophagic compartments during basal conditions. Ylä-Anttila P, et al. Autophagy, 2015. PMID 26325487, Free PMC Article
  3. Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells. Ding J, et al. Biochem Biophys Res Commun, 2003 Dec 19. PMID 14680817
  4. Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily. Olkkonen VM, et al. J Cell Sci, 1993 Dec. PMID 8126105
  5. The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum. Tambe Y, et al. Cancer Lett, 2009 Sep 28. PMID 19368996

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in autophagosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in autophagosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
ras-related protein Rab-24
Names
rab-16

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429097.1 → NP_001416026.1  ras-related protein Rab-24 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC160958

  2. NM_001429098.1 → NP_001416027.1  ras-related protein Rab-24 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC160958

  3. NM_001429099.1 → NP_001416028.1  ras-related protein Rab-24 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC160958

  4. NM_001429100.1 → NP_001416029.1  ras-related protein Rab-24 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC160958

  5. NM_001429101.1 → NP_001416030.1  ras-related protein Rab-24 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC160958

  6. NM_001429102.1 → NP_001416031.1  ras-related protein Rab-24 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC160958

  7. NM_001429103.1 → NP_001416032.1  ras-related protein Rab-24 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC160958

  8. NM_001429104.1 → NP_001416033.1  ras-related protein Rab-24 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC160958

  9. NM_001429105.1 → NP_001416034.1  ras-related protein Rab-24 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC160958

  10. NM_001429106.1 → NP_001416035.1  ras-related protein Rab-24 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC160958

  11. NM_001429107.1 → NP_001416036.1  ras-related protein Rab-24 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC160958

  12. NM_009000.4 → NP_033026.1  ras-related protein Rab-24 isoform 1

    See identical proteins and their annotated locations for NP_033026.1

    Status: VALIDATED

    Source sequence(s)
    AC160958
    Consensus CDS
    CCDS26541.1
    UniProtKB/Swiss-Prot
    P35290
    UniProtKB/TrEMBL
    Q0PD31, Q8K133
    Related
    ENSMUSP00000046188.8, ENSMUST00000035242.9
    Conserved Domains (1) summary
    cd04118
    Location:8 → 201
    Rab24; Rab GTPase family 24 (Rab24)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    55467036..55469807 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517165.5 → XP_006517228.1  ras-related protein Rab-24 isoform X1

    Conserved Domains (1) summary
    cd04118
    Location:8 → 183
    Rab24; Rab GTPase family 24 (Rab24)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P35290.2 GenPept UniProtKB/Swiss-Prot:P35290

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous