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Pabpc2 poly(A) binding protein, cytoplasmic 2 [ Mus musculus (house mouse) ]

Gene ID: 18459, updated on 9-Dec-2024

Summary

Official Symbol
Pabpc2provided by MGI
Official Full Name
poly(A) binding protein, cytoplasmic 2provided by MGI
Primary source
MGI:MGI:1349723
See related
Ensembl:ENSMUSG00000051732 AllianceGenome:MGI:1349723
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pabp; Pabp+; Pabp2
Summary
Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to act upstream of or within regulation of mRNA 3'-end processing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasmic stress granule; cytosol; and nucleus. Is expressed in brain; early conceptus; and gonad. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Pabpc2 in Genome Data Viewer
Location:
18 B3; 18 21.14 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (39906550..39909135)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (39773497..39776082)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30909 Neighboring gene predicted gene, 30961 Neighboring gene STARR-seq mESC enhancer starr_44404 Neighboring gene STARR-seq mESC enhancer starr_44405 Neighboring gene STARR-seq mESC enhancer starr_44406 Neighboring gene predicted gene, 41707 Neighboring gene STARR-seq mESC enhancer starr_44408 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:40026376-40026644 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:40037537-40037720 Neighboring gene predicted gene, 41708

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1)  1 citation

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA 3'-UTR binding  
enables poly(A) binding  
enables poly(A) binding PubMed 
enables poly(U) RNA binding  
Component Evidence Code Pubs
is_active_in cytoplasmic stress granule  
is_active_in cytosol  
is_active_in nucleus  
part_of ribonucleoprotein complex  

General protein information

Preferred Names
poly A binding protein, cytoplasmic 2
Names
poly A binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011033.2NP_035163.1  poly A binding protein, cytoplasmic 2

    See identical proteins and their annotated locations for NP_035163.1

    Status: VALIDATED

    Source sequence(s)
    AK077154, AV259277, BC051134, CN837699
    Consensus CDS
    CCDS29206.1
    UniProtKB/TrEMBL
    Q62029, Q792Y0
    Related
    ENSMUSP00000066639.3, ENSMUST00000063219.3
    Conserved Domains (1) summary
    TIGR01628
    Location:11607
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    39906550..39909135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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