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Or6e1 olfactory receptor family 6 subfamily E member 1 [ Mus musculus (house mouse) ]

Gene ID: 18348, updated on 5-Mar-2024

Summary

Official Symbol
Or6e1provided by MGI
Official Full Name
olfactory receptor family 6 subfamily E member 1provided by MGI
Primary source
MGI:MGI:1333764
See related
Ensembl:ENSMUSG00000048153 AllianceGenome:MGI:1333764
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IC6; Olfr49; MOR1181
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See Or6e1 in Genome Data Viewer
Location:
14 C2; 14 27.72 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (54519353..54520382, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (54281896..54282925, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene defender against cell death 1 Neighboring gene STARR-positive B cell enhancer ABC_E1168 Neighboring gene abhydrolase domain containing 4 Neighboring gene predicted gene 43305 Neighboring gene eukaryotic translation initiation factor 4H pseudogene

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables isoprenoid binding IDA
Inferred from Direct Assay
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables olfactory receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 6E1
Names
olfactory receptor 118-1
olfactory receptor 49
olfactory receptor I-C6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010991.2NP_035121.1  olfactory receptor 6E1

    See identical proteins and their annotated locations for NP_035121.1

    Status: VALIDATED

    Source sequence(s)
    BC145891
    Consensus CDS
    CCDS27085.1
    UniProtKB/Swiss-Prot
    Q8VFB7, Q9Z1V0
    Related
    ENSMUSP00000054361.5, ENSMUST00000059996.7
    Conserved Domains (2) summary
    pfam00001
    Location:39259
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29299
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    54519353..54520382 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)