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Myt1l myelin transcription factor 1-like [ Mus musculus (house mouse) ]

Gene ID: 17933, updated on 5-Mar-2024

Summary

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Official Symbol
Myt1lprovided by MGI
Official Full Name
myelin transcription factor 1-likeprovided by MGI
Primary source
MGI:MGI:1100511
See related
Ensembl:ENSMUSG00000061911 AllianceGenome:MGI:1100511
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nztf1; Pmng1; Png-1; mKIAA1106; 2900046C06Rik; 2900093J19Rik; C630034G21Rik
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II; neuron development; and neuron fate specification. Located in nucleus. Is expressed in several structures, including eye; genitourinary system; nervous system; and olfactory epithelium. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 9.3), frontal lobe adult (RPKM 8.6) and 6 other tissues See more
Orthologs
human all
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Genomic context

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Location:
12 A2; 12 11.86 cM
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (29578375..29973215)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (29527590..29923216)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31650 Neighboring gene STARR-seq mESC enhancer starr_31832 Neighboring gene predicted gene, 53714 Neighboring gene predicted gene, 20208 Neighboring gene STARR-seq mESC enhancer starr_31833 Neighboring gene STARR-seq mESC enhancer starr_31834 Neighboring gene RIKEN cDNA C630031E19 gene Neighboring gene predicted gene, 53715 Neighboring gene predicted gene, 46346 Neighboring gene predicted gene, 31939 Neighboring gene STARR-seq mESC enhancer starr_31838 Neighboring gene peroxidasin Neighboring gene STARR-seq mESC enhancer starr_31839 Neighboring gene STARR-seq mESC enhancer starr_31840 Neighboring gene predicted gene 15691 Neighboring gene thyroid peroxidase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain. Chen J, et al. Genome Res, 2023 Apr. PMID 37100461, Free PMC Article
  2. Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination. Shi Y, et al. Neurosci Bull, 2018 Apr. PMID 29397565, Free PMC Article
  3. Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development. Weiner JA, et al. J Comp Neurol, 1997 May 5. PMID 9130664
  4. Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca(2+) Sensitivity of Insulin Secretion Vesicles. Huang C, et al. Dev Cell, 2018 May 7. PMID 29656931, Free PMC Article
  5. Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates. Mall M, et al. Nature, 2017 Apr 13. PMID 28379941

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
    Title: MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
  2. MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain.
    Title: MYT1L is required for suppressing earlier neuronal development programs in the adult mouse brain.
  3. Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice.
    Title: Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice.
  4. Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice.
    Title: Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice.
  5. A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.
    Title: A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.
  6. our findings demonstrate that Myt1L is an essential regulator of oligodendrocyte precursor cell differentiation
    Title: Myt1L Promotes Differentiation of Oligodendrocyte Precursor Cells and is Necessary for Remyelination After Lysolecithin-Induced Demyelination.
  7. Depletion of Myt1l in primary postmitotic neurons de-repressed non-neuronal programs and impaired neuronal gene expression and function, indicating that many somatic lineage programs are actively and persistently repressed by Myt1l to maintain neuronal identity.
    Title: Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.
  8. NZF-1 was expressed later in post-mitotic neurons. NZF-2 was initially expressed in neuronal cells a little earlier than NZF-3. NZF-3 was initially expressed in neuronal cells, just after proliferation was complete.
    Title: Spatiotemporal expression pattern of Myt/NZF family zinc finger transcription factors during mouse nervous system development.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
  
enables cobalt ion binding ISO
Inferred from Sequence Orthology
more info
  
enables ion binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion sequestering activity ISO
Inferred from Sequence Orthology
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables retinoic acid-responsive element binding ISO
Inferred from Sequence Orthology
more info
  
enables transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
  
enables zinc ion binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in nervous system development IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuron development IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuron differentiation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuron fate commitment IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuron fate specification IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
myelin transcription factor 1-like protein
Names
NZF-1
myT1-L
neural zinc finger factor 1
neural zinc finger protein NZF-1
neural zinc finger transcription factor 1
postmeiotic neural gene 1
postmitotic neural gene 1 protein
zinc finger protein Png-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001093775.1 → NP_001087244.1  myelin transcription factor 1-like protein isoform 1

    See identical proteins and their annotated locations for NP_001087244.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK013654, BC094438, BE653129, BQ876229, CB521730, CD802997, CX240996
    Consensus CDS
    CCDS49042.1
    UniProtKB/Swiss-Prot
    A2RRK5, D3Z1P7, O08996, P97500, Q33DP0, Q8C643, Q8C7L4, Q8CHB4
    UniProtKB/TrEMBL
    Q0VGN2
    Related
    ENSMUSP00000058264.10, ENSMUST00000049784.17
    Conserved Domains (3) summary
    COG1196
    Location:1034 → 1186
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  2. NM_001093776.1 → NP_001087245.1  myelin transcription factor 1-like protein isoform 2

    See identical proteins and their annotated locations for NP_001087245.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Variants 2, 3, 6 and 7 encode the same isoform (2).
    Source sequence(s)
    AK013654, BC079651, BC094438, CD352642, CX240996
    Consensus CDS
    CCDS49041.1
    UniProtKB/TrEMBL
    Q0VGN2
    Related
    ENSMUSP00000021009.9, ENSMUST00000021009.10
    Conserved Domains (3) summary
    COG1196
    Location:1032 → 1184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  3. NM_001093778.1 → NP_001087247.1  myelin transcription factor 1-like protein isoform 3

    See identical proteins and their annotated locations for NP_001087247.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses alternate in-frame splice sites in the 5' and mid-coding regions, compared to variant 1, resulting in a shorter protein (isoform 3).
    Source sequence(s)
    AK013654, BC094438, BE653129, BQ876229, CB521730, CF536651, CX240996
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    pfam01530
    Location:902 → 928
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:619 → 870
    MYT1; Myelin transcription factor 1
    pfam10267
    Location:1054 → 1126
    Tmemb_cc2; Predicted transmembrane and coiled-coil 2 protein

  4. NM_001361655.1 → NP_001348584.1  myelin transcription factor 1-like protein isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC159626, AK013654, BB618038, BC079651, BC094438, BE653129, CD802997, CF746282, CX240996
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  5. NM_001361656.1 → NP_001348585.1  myelin transcription factor 1-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK013654, BC079651, BC094438, CJ070076, CX240996
    Consensus CDS
    CCDS49041.1
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1032 → 1184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  6. NM_001361657.1 → NP_001348586.1  myelin transcription factor 1-like protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK013654, BC079651, BC094438, BY124359, CX240996
    Consensus CDS
    CCDS49041.1
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1032 → 1184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  7. NM_001361658.1 → NP_001348587.1  myelin transcription factor 1-like protein isoform 5

    Status: VALIDATED

    Source sequence(s)
    AK013654, BC079651, BC094438, BE653129, CB521730, CX240996
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1011 → 1163
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:882 → 910
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:599 → 850
    MYT1; Myelin transcription factor 1

  8. NM_001361659.1 → NP_001348588.1  myelin transcription factor 1-like protein isoform 6

    Status: VALIDATED

    Source sequence(s)
    AK013654, BC079651, BC094438, BE653129, CB521730, CX240996
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:987 → 1139
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:858 → 886
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:575 → 826
    MYT1; Myelin transcription factor 1

  9. NM_001361660.1 → NP_001348589.1  myelin transcription factor 1-like protein isoform 7

    Status: VALIDATED

    Source sequence(s)
    AK013654, BC079651, BC094438, BE653129, CB521730, CX240996
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:984 → 1118
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:837 → 865
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:554 → 805
    MYT1; Myelin transcription factor 1

  10. NM_008666.3 → NP_032692.2  myelin transcription factor 1-like protein isoform 2

    See identical proteins and their annotated locations for NP_032692.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2). Variants 2, 3, 6 and 7 encode the same isoform (2).
    Source sequence(s)
    AK013654, BC094438, BE653129, BQ876229, CB521730, CX240996
    Consensus CDS
    CCDS49041.1
    UniProtKB/TrEMBL
    Q0VGN2
    Related
    ENSMUSP00000151588.2, ENSMUST00000218583.2
    Conserved Domains (3) summary
    COG1196
    Location:1032 → 1184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    29578375..29973215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011243823.4 → XP_011242125.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011242125.1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  2. XM_030246587.2 → XP_030102447.1  myelin transcription factor 1-like protein isoform X4

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1032 → 1184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  3. XM_011243819.4 → XP_011242121.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011242121.1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  4. XM_030246582.2 → XP_030102442.1  myelin transcription factor 1-like protein isoform X3

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1059 → 1137
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  5. XM_030246588.2 → XP_030102448.1  myelin transcription factor 1-like protein isoform X5

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1013 → 1167
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:884 → 912
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:601 → 852
    MYT1; Myelin transcription factor 1

  6. XM_036157214.1 → XP_036013107.1  myelin transcription factor 1-like protein isoform X7

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1011 → 1165
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:882 → 910
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:599 → 850
    MYT1; Myelin transcription factor 1

  7. XM_030246594.2 → XP_030102454.1  myelin transcription factor 1-like protein isoform X16

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:868 → 1022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:739 → 767
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:456 → 707
    MYT1; Myelin transcription factor 1

  8. XM_030246596.2 → XP_030102456.1  myelin transcription factor 1-like protein isoform X17

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:866 → 1020
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:737 → 765
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:454 → 705
    MYT1; Myelin transcription factor 1

  9. XM_036157213.1 → XP_036013106.1  myelin transcription factor 1-like protein isoform X5

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1013 → 1167
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:884 → 912
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:601 → 852
    MYT1; Myelin transcription factor 1

  10. XM_030246584.2 → XP_030102444.1  myelin transcription factor 1-like protein isoform X3

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1059 → 1137
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  11. XM_030246592.2 → XP_030102452.1  myelin transcription factor 1-like protein isoform X16

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:868 → 1022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:739 → 767
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:456 → 707
    MYT1; Myelin transcription factor 1

  12. XM_011243820.4 → XP_011242122.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011242122.1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  13. XM_011243818.4 → XP_011242120.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011242120.1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  14. XM_011243833.4 → XP_011242135.1  myelin transcription factor 1-like protein isoform X9

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  15. XM_011243827.4 → XP_011242129.1  myelin transcription factor 1-like protein isoform X2

    See identical proteins and their annotated locations for XP_011242129.1

    UniProtKB/Swiss-Prot
    A2RRK5, D3Z1P7, O08996, P97500, Q33DP0, Q8C643, Q8C7L4, Q8CHB4
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1034 → 1186
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  16. XM_030246581.2 → XP_030102441.1  myelin transcription factor 1-like protein isoform X3

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1059 → 1137
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  17. XM_030246591.2 → XP_030102451.1  myelin transcription factor 1-like protein isoform X11

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1059 → 1137
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  18. XM_036157215.1 → XP_036013108.1  myelin transcription factor 1-like protein isoform X13

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:987 → 1141
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:858 → 886
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:575 → 826
    MYT1; Myelin transcription factor 1

  19. XM_017314976.3 → XP_017170465.1  myelin transcription factor 1-like protein isoform X14

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:987 → 1139
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:858 → 886
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:575 → 826
    MYT1; Myelin transcription factor 1

  20. XM_017314980.3 → XP_017170469.1  myelin transcription factor 1-like protein isoform X16

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:868 → 1022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:739 → 767
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:456 → 707
    MYT1; Myelin transcription factor 1

  21. XM_030246595.2 → XP_030102455.1  myelin transcription factor 1-like protein isoform X17

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:866 → 1020
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:737 → 765
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:454 → 705
    MYT1; Myelin transcription factor 1

  22. XM_011243831.4 → XP_011242133.1  myelin transcription factor 1-like protein isoform X5

    See identical proteins and their annotated locations for XP_011242133.1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1013 → 1167
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:884 → 912
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:601 → 852
    MYT1; Myelin transcription factor 1

  23. XM_030246589.2 → XP_030102449.1  myelin transcription factor 1-like protein isoform X6

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1013 → 1165
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:884 → 912
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:601 → 852
    MYT1; Myelin transcription factor 1

  24. XM_017314971.3 → XP_017170460.1  myelin transcription factor 1-like protein isoform X7

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1011 → 1165
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:882 → 910
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:599 → 850
    MYT1; Myelin transcription factor 1

  25. XM_017314972.3 → XP_017170461.1  myelin transcription factor 1-like protein isoform X8

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1011 → 1163
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:882 → 910
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:599 → 850
    MYT1; Myelin transcription factor 1

  26. XM_017314978.3 → XP_017170467.1  myelin transcription factor 1-like protein isoform X15

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:984 → 1118
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:837 → 865
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:554 → 805
    MYT1; Myelin transcription factor 1

  27. XM_011243834.4 → XP_011242136.1  myelin transcription factor 1-like protein isoform X10

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam05667
    Location:893 → 1118
    DUF812; Protein of unknown function (DUF812)
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  28. XM_017314974.3 → XP_017170463.1  myelin transcription factor 1-like protein isoform X12

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam05667
    Location:891 → 1116
    DUF812; Protein of unknown function (DUF812)
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  29. XM_036157218.1 → XP_036013111.1  myelin transcription factor 1-like protein isoform X18

    Conserved Domains (2) summary
    pfam01530
    Location:30 → 58
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  30. XM_036157219.1 → XP_036013112.1  myelin transcription factor 1-like protein isoform X19

    Conserved Domains (2) summary
    pfam01530
    Location:30 → 58
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  31. XM_011243824.4 → XP_011242126.1  myelin transcription factor 1-like protein isoform X1

    See identical proteins and their annotated locations for XP_011242126.1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  32. XM_030246585.2 → XP_030102445.1  myelin transcription factor 1-like protein isoform X3

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1059 → 1137
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  33. XM_036157216.1 → XP_036013109.1  myelin transcription factor 1-like protein isoform X16

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:868 → 1022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:739 → 767
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:456 → 707
    MYT1; Myelin transcription factor 1

  34. XM_036157217.1 → XP_036013110.1  myelin transcription factor 1-like protein isoform X17

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:866 → 1020
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:737 → 765
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:454 → 705
    MYT1; Myelin transcription factor 1

  35. XM_030246576.2 → XP_030102436.1  myelin transcription factor 1-like protein isoform X1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1061 → 1139
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  36. XM_036157211.1 → XP_036013104.1  myelin transcription factor 1-like protein isoform X2

    UniProtKB/Swiss-Prot
    A2RRK5, D3Z1P7, O08996, P97500, Q33DP0, Q8C643, Q8C7L4, Q8CHB4
    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1034 → 1186
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:905 → 933
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:622 → 873
    MYT1; Myelin transcription factor 1

  37. XM_030246583.2 → XP_030102443.1  myelin transcription factor 1-like protein isoform X3

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    TIGR04211
    Location:1059 → 1137
    SH3_and_anchor; SH3 domain protein
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1

  38. XM_030246593.2 → XP_030102453.1  myelin transcription factor 1-like protein isoform X16

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:868 → 1022
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:739 → 767
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:456 → 707
    MYT1; Myelin transcription factor 1

  39. XM_011243832.4 → XP_011242134.1  myelin transcription factor 1-like protein isoform X5

    See identical proteins and their annotated locations for XP_011242134.1

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1013 → 1167
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:884 → 912
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:601 → 852
    MYT1; Myelin transcription factor 1

  40. XM_030246590.2 → XP_030102450.1  myelin transcription factor 1-like protein isoform X7

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1011 → 1165
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:882 → 910
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:599 → 850
    MYT1; Myelin transcription factor 1

  41. XM_036157212.1 → XP_036013105.1  myelin transcription factor 1-like protein isoform X4

    UniProtKB/TrEMBL
    Q0VGN2
    Conserved Domains (3) summary
    COG1196
    Location:1032 → 1184
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam01530
    Location:903 → 931
    zf-C2HC; Zinc finger, C2HC type
    pfam08474
    Location:620 → 871
    MYT1; Myelin transcription factor 1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P97500.3 GenPept UniProtKB/Swiss-Prot:P97500

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