U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

zip-4 Transcription factor zip-4 [ Caenorhabditis elegans ]

Gene ID: 171900, updated on 23-Nov-2023

Summary

Go to the top of the page Help
Gene symbol
zip-4
Gene description
Transcription factor zip-4
Primary source
WormBase:WBGene00021552
Locus tag
CELE_Y44E3B.1
See related
AllianceGenome:WB:WBGene00021552
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in nucleus. Is expressed in gonad; pharynx; and vulva. [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (3264111..3266762, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Tyrosinase copper-binding domain-containing protein Neighboring gene Nop domain-containing protein Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa. Tjahjono E, et al. PLoS Genet, 2017 Jun. PMID 28662060, Free PMC Article
  2. Networks of bZIP protein-protein interactions diversified over a billion years of evolution. Reinke AW, et al. Science, 2013 May 10. PMID 23661758, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response to Gram-negative bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Transcription factor zip-4
NP_001040703.1
  • Confirmed by transcript evidence
NP_001368002.1
  • Confirmed by transcript evidence
NP_491133.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3264111..3266762 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001381600.2 → NP_001368002.1  Transcription factor zip-4 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G4SR45, H2L0N3, Q965I4
    Conserved Domains (2) summary
    cd14686
    Location:231 → 294
    bZIP; coiled coil [structural motif]
    cl21462
    Location:231 → 294
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  2. NM_058732.5 → NP_491133.1  Transcription factor zip-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491133.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q965I4
    Conserved Domains (2) summary
    cd14686
    Location:231 → 294
    bZIP; coiled coil [structural motif]
    cl21462
    Location:231 → 294
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  3. NM_001047238.7 → NP_001040703.1  Transcription factor zip-4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001040703.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G4SR45
    Conserved Domains (2) summary
    cd14686
    Location:168 → 231
    bZIP; coiled coil [structural motif]
    cl21462
    Location:168 → 231
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
H2L0N3.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Tools