DNAJB1P1 DNAJB1 pseudogene 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: DNAJB1P1provided by HGNC
Official Full Name: DNAJB1 pseudogene 1provided by HGNC
Primary source: HGNC:HGNC:24988
See related: AllianceGenome:HGNC:24988
Gene type: pseudo
RefSeq status: INFERRED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: HSP40; DNAJB1P; psiHSP40
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Genomic context

Location:: 2q32.3

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	2	NC_000002.12 (191879992..191882253, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	2	NC_060926.1 (192368214..192370475, complement)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	2	NC_000002.11 (192744718..192746979, complement)

Chromosome 2 - NC_000002.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that GM significantly suppressed refolding of firefly luciferase in the presence of HSP70 and HSP40.
Title: Gentamicin inhibits HSP70-assisted protein folding by interfering with substrate recognition.
Impairment of beta cells is mostly linked with the aggregate formation of mutant huntingtin, and that HSP40 ameliorates the malfunction of pancreatic beta cells by inhibiting aggregation.
Title: HSP40 ameliorates impairment of insulin secretion by inhibiting huntingtin aggregation in a HD pancreatic beta cell model.
Hsp 70 and Hsp 40 may be tumor markers for colorectal cancer.
Title: Expression of heat shock protein (Hsp) 70 and Hsp 40 in colorectal cancer.
Overexpressed in gastric cancer
Title: Expression of heat shock protein (Hsp) 70 and Hsp 40 in gastric cancer.
Results report cooperative interactions involving Hsp70, Hsp40, and TPR1 that enhance Hsp70-dependent folding of chemically denatured substrates.
Title: Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Other Names

DnaJ (Hsp40) homolog, subfamily B, member 1 pseudogene 1
DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1
HSP40 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.