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Ltb4r1 leukotriene B4 receptor 1 [ Mus musculus (house mouse) ]

Gene ID: 16995, updated on 11-Apr-2024

Summary

Official Symbol
Ltb4r1provided by MGI
Official Full Name
leukotriene B4 receptor 1provided by MGI
Primary source
MGI:MGI:1309472
See related
Ensembl:ENSMUSG00000046908 AllianceGenome:MGI:1309472
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BLT1; BLTR; Ltb4r; mBLTR; LTB4-R1
Summary
Enables leukotriene B4 receptor activity. Acts upstream of or within signal transduction. Predicted to be located in membrane raft. Predicted to be integral component of plasma membrane. Is expressed in brain and lateral ventricle. Orthologous to human LTB4R (leukotriene B4 receptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in duodenum adult (RPKM 10.3), small intestine adult (RPKM 8.5) and 12 other tissues See more
Orthologs
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Genomic context

See Ltb4r1 in Genome Data Viewer
Location:
14 C3; 14 28.19 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (56002154..56005951)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (55765962..55768492)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene NOP9 nucleolar protein Neighboring gene cell death-inducing DNA fragmentation factor, alpha subunit-like effector B Neighboring gene STARR-seq mESC enhancer starr_36778 Neighboring gene leukotriene B4 receptor 2 Neighboring gene adenylate cyclase 4 Neighboring gene predicted gene, 32092 Neighboring gene receptor-interacting serine-threonine kinase 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (6)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled peptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables leukotriene B4 receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables leukotriene B4 receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables leukotriene receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in neuropeptide signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
leukotriene B4 receptor 1
Names
LTB4 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001411957.1NP_001398886.1  leukotriene B4 receptor 1

    Status: VALIDATED

    Source sequence(s)
    AC098877
    UniProtKB/Swiss-Prot
    O88855
    UniProtKB/TrEMBL
    A7VJD3
  2. NM_008519.3NP_032545.1  leukotriene B4 receptor 1

    See identical proteins and their annotated locations for NP_032545.1

    Status: VALIDATED

    Source sequence(s)
    AC098877
    Consensus CDS
    CCDS27129.1
    UniProtKB/Swiss-Prot
    O88855
    UniProtKB/TrEMBL
    A7VJD3
    Related
    ENSMUSP00000051368.4, ENSMUST00000057569.4
    Conserved Domains (1) summary
    pfam00001
    Location:37285
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    56002154..56005951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)