Krtap6-2 keratin associated protein 6-2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Krtap6-2provided by MGI
Official Full Name: keratin associated protein 6-2provided by MGI
Primary source: MGI:MGI:1330280
See related: Ensembl:ENSMUSG00000062433 AllianceGenome:MGI:1330280
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: HGTpII.4
Summary: Predicted to be involved in hair follicle development. Predicted to be located in intermediate filament. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 16 C3.3; 16 51.42 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (89216211..89216999, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (89419323..89420111, complement)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

K6alpha, K6beta, and K17 have roles in normal development of the nail bed epithelium
Title: Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.
Krtap16 is a hair keratin-associated protein gene complex regulated by Hoxc13; localized to chromosome 16
Title: Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:493101

AI646275 (e-PCR)
- UniSTS:180940

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in hair follicle development	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in intermediate filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin-associated protein 6-2

Names: HGTp type II.4; high-glycine tyrosine keratin type II.4; keratin-associated protein 6.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.