Kif9 kinesin family member 9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Kif9provided by MGI
Official Full Name: kinesin family member 9provided by MGI
Primary source: MGI:MGI:1098237
See related: Ensembl:ENSMUSG00000032489 AllianceGenome:MGI:1098237
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable several functions, including ATP hydrolysis activity; identical protein binding activity; and microtubule binding activity. Predicted to be involved in several processes, including extracellular matrix disassembly; organelle disassembly; and regulation of podosome assembly. Predicted to be located in podosome and vesicle. Predicted to be part of kinesin complex. Predicted to be active in microtubule. Is expressed in lateral ventricle choroid plexus and metencephalon part of 4th ventricle choroid plexus. Orthologous to human KIF9 (kinesin family member 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 35.4) and lung adult (RPKM 1.2) See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 9 F2; 9 59.92 cM

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (110306062..110354242)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (110476738..110525174)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum.
Title: The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum.

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (8) 1 citation

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule motor activity	IBA Inferred from Biological aspect of Ancestor more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in extracellular matrix disassembly	ISO Inferred from Sequence Orthology more info
involved_in microtubule-based movement	IBA Inferred from Biological aspect of Ancestor more info
involved_in organelle disassembly	ISO Inferred from Sequence Orthology more info
involved_in regulation of flagellated sperm motility	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of podosome assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cilium	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in cytosol	TAS Traceable Author Statement more info
part_of kinesin complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	ISO Inferred from Sequence Orthology more info
located_in motile cilium	IEA Inferred from Electronic Annotation more info
located_in podosome	ISO Inferred from Sequence Orthology more info
located_in sperm flagellum	IDA Inferred from Direct Assay more info	PubMed
located_in vesicle	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: kinesin-like protein KIF9

Names: kinesin 9

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001163569.2 → NP_001157041.1 kinesin-like protein KIF9 isoform 1

See identical proteins and their annotated locations for NP_001157041.1

Status: VALIDATED

Source sequence(s)

AC132103

Consensus CDS

CCDS52938.1

UniProtKB/TrEMBL

Q3V3Y6, Q8C0X6

Related

ENSMUSP00000057896.7, ENSMUST00000061155.12

Conserved Domains (1) summary

cd01375
Location:6 → 338

KISc_KIF9_like; Kinesin motor domain, KIF9-like subgroup
NM_001411177.1 → NP_001398106.1 kinesin-like protein KIF9 isoform 1

Status: VALIDATED

Source sequence(s)

AC132103

UniProtKB/TrEMBL

Q8C0X6
NM_001411178.1 → NP_001398107.1 kinesin-like protein KIF9 isoform 2

Status: VALIDATED

Source sequence(s)

AC132103

UniProtKB/Swiss-Prot

E9QMT7, O35070, Q9WV04
NM_001411179.1 → NP_001398108.1 kinesin-like protein KIF9 isoform 3

Status: VALIDATED

Source sequence(s)

AC132103
NM_001411180.1 → NP_001398109.1 kinesin-like protein KIF9 isoform 4

Status: VALIDATED

Source sequence(s)

AC132103
NM_010628.4 → NP_034758.2 kinesin-like protein KIF9 isoform 2

See identical proteins and their annotated locations for NP_034758.2

Status: VALIDATED

Source sequence(s)

AC132103

Consensus CDS

CCDS23568.1

UniProtKB/Swiss-Prot

E9QMT7, O35070, Q9WV04

UniProtKB/TrEMBL

Q3V3Y6

Related

ENSMUSP00000082016.6, ENSMUST00000084952.8

Conserved Domains (2) summary

cd01375
Location:6 → 338

KISc_KIF9_like; Kinesin motor domain, KIF9-like subgroup

pfam00225
Location:12 → 340

Kinesin; Kinesin motor domain