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Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 [ Mus musculus (house mouse) ]

Gene ID: 16516, updated on 11-Apr-2024

Summary

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Official Symbol
Kcnj15provided by MGI
Official Full Name
potassium inwardly-rectifying channel, subfamily J, member 15provided by MGI
Primary source
MGI:MGI:1310000
See related
Ensembl:ENSMUSG00000062609 AllianceGenome:MGI:1310000
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IRKK; Kir4.2; 4930414N08Rik
Summary
Enables potassium channel activity. Acts upstream of or within potassium ion transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to human KCNJ15 (potassium inwardly rectifying channel subfamily J member 15). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 32.3), lung adult (RPKM 4.3) and 2 other tissues See more
Orthologs
human all
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Genomic context

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Location:
16 C4; 16 55.86 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (95058417..95101119)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (95257558..95300260)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_41599 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene predicted gene, 31641 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:95484660-95484843 Neighboring gene predicted gene, 31754 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95563080-95563380 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95572113-95572413 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95581838-95582139 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95649181-95649482 Neighboring gene STARR-positive B cell enhancer mm9_chr16:95650074-95650374 Neighboring gene ETS transcription factor Neighboring gene STARR-seq mESC enhancer starr_41600 Neighboring gene STARR-seq mESC enhancer starr_41602 Neighboring gene predicted gene, 31845

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion. Bignon Y, et al. Kidney Int, 2020 Feb. PMID 31870500
  2. Acid secretion-associated translocation of KCNJ15 in gastric parietal cells. He W, et al. Am J Physiol Gastrointest Liver Physiol, 2011 Oct. PMID 21719736, Free PMC Article
  3. Developmentally regulated expression of the murine ortholog of the potassium channel KIR4.2 (KCNJ15). Thiery E, et al. Mech Dev, 2000 Jul. PMID 10906485
  4. Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice. Stern S, et al. EBioMedicine, 2015 Sep. PMID 26501103, Free PMC Article
  5. A new inward rectifier potassium channel gene (KCNJ15) localized on chromosome 21 in the Down syndrome chromosome region 1 (DCR1). Gosset P, et al. Genomics, 1997 Sep 1. PMID 9299242

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na[+] Channel (ENaC).
    Title: Role of Angiotensin II Type 1a Receptor (AT1aR) of Renal Tubules in Regulating Inwardly Rectifying Potassium Channels 4.2 (Kir4.2), Kir4.1, and Epithelial Na(+) Channel (ENaC).
  2. Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa.
    Title: Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa.
  3. Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion.
    Title: Defective bicarbonate reabsorption in Kir4.2 potassium channel deficient mice impairs acid-base balance and ammonia excretion.
  4. Data show that KCNJ15 inward rectifier potassium channel and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents are changed in Trisomic neuron.
    Title: Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice.
  5. It was shown that downregulation of Kcnj15 leads to increased insulin secretion in vitro and in vivo. The mechanism for regulating insulin secretion inolved a calcium-sensiong receptor.
    Title: Inhibition of glucose-stimulated insulin secretion by KCNJ15, a newly identified susceptibility gene for type 2 diabetes.
  6. in nonsecreting parietal cells, KCNJ15 is stored in vesicles distinct from the H(+)-K(+)-ATPase-enriched tubulovesicles. Furthermore, upon stimulation, KCNJ15 and H(+)-K(+)-ATPase both translocate to the apical membrane for active acid secretion.
    Title: Acid secretion-associated translocation of KCNJ15 in gastric parietal cells.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (3) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables inward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables inward rectifier potassium channel activity ISO
Inferred from Sequence Orthology
more info
  
enables potassium channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within potassium ion transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within potassium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of monoatomic ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IC
Inferred by Curator
more info
 PubMed 
part_of monoatomic ion channel complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ATP-sensitive inward rectifier potassium channel 15
Names
inward rectifier K+ channel Kir4.2
potassium channel, inwardly rectifying subfamily J member 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039056.2 → NP_001034145.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001034145.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Related
    ENSMUSP00000109485.2, ENSMUST00000113854.8
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

  2. NM_001039057.2 → NP_001034146.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001034146.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform a. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AI116801, AK165436
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Related
    ENSMUSP00000045218.8, ENSMUST00000037154.14
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  3. NM_001271687.1 → NP_001258616.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258616.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AI891955, AK165436
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  4. NM_001271689.1 → NP_001258618.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258618.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154546, AC154691
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Related
    ENSMUSP00000109486.2, ENSMUST00000113855.8
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

  5. NM_001271690.1 → NP_001258619.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258619.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AK165346, AK165436
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Related
    ENSMUSP00000109492.2, ENSMUST00000113861.8
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  6. NM_001271691.1 → NP_001258620.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258620.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436, AW012236
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

  7. NM_001271692.1 → NP_001258621.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258621.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154546, AC154691
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  8. NM_001271693.1 → NP_001258622.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258622.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436, AW258994, AY377988
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

  9. NM_001271694.1 → NP_001258623.1  ATP-sensitive inward rectifier potassium channel 15 isoform a

    See identical proteins and their annotated locations for NP_001258623.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 1. Variants 1, 4, 6, 8, and 10 encode the same isoform (a).
    Source sequence(s)
    AC154691, AK165436, AW319416
    Consensus CDS
    CCDS28351.1
    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  10. NM_001271695.1 → NP_001258624.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_001258624.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AI891955, AK165436, BB843850
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

  11. NM_019664.5 → NP_062638.1  ATP-sensitive inward rectifier potassium channel 15 isoform b

    See identical proteins and their annotated locations for NP_062638.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2, 3, 5, 7, 9 and 11 encode the same isoform (b).
    Source sequence(s)
    AC154691, AK165436, AW260030, AY377988
    Consensus CDS
    CCDS37410.1
    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Related
    ENSMUSP00000109487.2, ENSMUST00000113856.8
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

RNA

  1. NR_073406.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12) uses an alternate splice site and two alternate internal exons, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC154546, AC154691

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    95058417..95101119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522944.3 → XP_006523007.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    See identical proteins and their annotated locations for XP_006523007.1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Related
    ENSMUSP00000109493.2, ENSMUST00000113862.8
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  2. XM_006522951.4 → XP_006523014.1  ATP-sensitive inward rectifier potassium channel 15 isoform X3

    See identical proteins and their annotated locations for XP_006523014.1

    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

  3. XM_006522942.4 → XP_006523005.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    See identical proteins and their annotated locations for XP_006523005.1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  4. XM_006522950.4 → XP_006523013.1  ATP-sensitive inward rectifier potassium channel 15 isoform X2

    See identical proteins and their annotated locations for XP_006523013.1

    UniProtKB/TrEMBL
    Q3TR79
    Conserved Domains (2) summary
    pfam01007
    Location:46 → 187
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:194 → 365
    IRK_C; Inward rectifier potassium channel C-terminal domain

  5. XM_006522945.4 → XP_006523008.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    See identical proteins and their annotated locations for XP_006523008.1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  6. XM_017316883.2 → XP_017172372.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Related
    ENSMUSP00000109490.2, ENSMUST00000113859.8
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  7. XM_017316885.1 → XP_017172374.1  ATP-sensitive inward rectifier potassium channel 15 isoform X3

    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Related
    ENSMUSP00000109489.3, ENSMUST00000113858.3
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain

  8. XM_036159796.1 → XP_036015689.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  9. XM_017316884.1 → XP_017172373.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  10. XM_006522947.3 → XP_006523010.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    See identical proteins and their annotated locations for XP_006523010.1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  11. XM_006522946.4 → XP_006523009.1  ATP-sensitive inward rectifier potassium channel 15 isoform X1

    See identical proteins and their annotated locations for XP_006523009.1

    UniProtKB/TrEMBL
    B7ZNJ9, Q3TNE6, Q3TR79, Q3UQ02
    Conserved Domains (2) summary
    pfam01007
    Location:57 → 198
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:205 → 376
    IRK_C; Inward rectifier potassium channel C-terminal domain

  12. XM_006522952.5 → XP_006523015.1  ATP-sensitive inward rectifier potassium channel 15 isoform X3

    See identical proteins and their annotated locations for XP_006523015.1

    UniProtKB/Swiss-Prot
    O88932, Q9JK34
    UniProtKB/TrEMBL
    Q3TR79, Q53Z04
    Conserved Domains (2) summary
    pfam01007
    Location:30 → 171
    IRK; Inward rectifier potassium channel
    pfam17655
    Location:178 → 349
    IRK_C; Inward rectifier potassium channel C-terminal domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O88932.1 GenPept UniProtKB/Swiss-Prot:O88932

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