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Ipp IAP promoted placental gene [ Mus musculus (house mouse) ]

Gene ID: 16351, updated on 5-Mar-2024

Summary

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Official Symbol
Ippprovided by MGI
Official Full Name
IAP promoted placental geneprovided by MGI
Primary source
MGI:MGI:96581
See related
Ensembl:ENSMUSG00000028696 AllianceGenome:MGI:96581
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mipp; D4Jhu8
Summary
Predicted to enable actin binding activity. Predicted to be located in cytoplasm and cytoskeleton. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and yolk sac endoderm. Orthologous to human IPP (intracisternal A particle-promoted polypeptide). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 3.6), liver E14.5 (RPKM 2.9) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 D1; 4 53.2 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116364710..116400607)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116507512..116543410)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene phosphoinositide-3-kinase regulatory subunit 3 Neighboring gene STARR-seq mESC enhancer starr_11136 Neighboring gene BRCA1 associated RING domain 1 pseudogene Neighboring gene microtubule associated serine/threonine kinase 2 Neighboring gene STARR-seq mESC enhancer starr_11138 Neighboring gene predicted gene, 52760 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:116180277-116180386 Neighboring gene STARR-seq mESC enhancer starr_11140 Neighboring gene transmembrane protein 69 Neighboring gene GC-rich promoter binding protein 1-like 1 Neighboring gene RIKEN cDNA C530005A16 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
actin-binding protein IPP
Names
intracisternal A particle-promoted polypeptide
murine IAP-promoted placenta-expressed protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418990.1 → NP_001405919.1  actin-binding protein IPP isoform b

    Status: VALIDATED

    Source sequence(s)
    AL669953

  2. NM_001418991.1 → NP_001405920.1  actin-binding protein IPP isoform c

    Status: VALIDATED

    Source sequence(s)
    AL669953

  3. NM_001418992.1 → NP_001405921.1  actin-binding protein IPP isoform d

    Status: VALIDATED

    Source sequence(s)
    AL669953

  4. NM_001418993.1 → NP_001405922.1  actin-binding protein IPP isoform d

    Status: VALIDATED

    Source sequence(s)
    AL669953

  5. NM_008389.4 → NP_032415.2  actin-binding protein IPP isoform a

    See identical proteins and their annotated locations for NP_032415.2

    Status: VALIDATED

    Source sequence(s)
    AL669953
    Consensus CDS
    CCDS38851.1
    UniProtKB/Swiss-Prot
    P28575, Q3V2M0
    Related
    ENSMUSP00000102088.2, ENSMUST00000106479.8
    Conserved Domains (3) summary
    PHA03098
    Location:34 → 575
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:333 → 376
    Kelch; KELCH repeat [structural motif]
    cd18256
    Location:17 → 141
    BTB_POZ_KLHL27_IPP; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in intracisternal A particle-promoted polypeptide (IPP)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    116364710..116400607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502810.5 → XP_006502873.1  actin-binding protein IPP isoform X1

    Conserved Domains (4) summary
    PHA03098
    Location:34 → 540
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:333 → 376
    Kelch; KELCH repeat [structural motif]
    cd18256
    Location:17 → 141
    BTB_POZ_KLHL27_IPP; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in intracisternal A particle-promoted polypeptide (IPP)
    cd18466
    Location:134 → 236
    BACK_KLHL27_IPP; BACK (BTB and C-terminal Kelch) domain found in intracisternal A particle-promoted polypeptide (IPP)

  2. XM_036163740.1 → XP_036019633.1  actin-binding protein IPP isoform X2

    Conserved Domains (4) summary
    PHA03098
    Location:34 → 540
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:333 → 376
    Kelch; KELCH repeat [structural motif]
    cd18256
    Location:17 → 141
    BTB_POZ_KLHL27_IPP; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in intracisternal A particle-promoted polypeptide (IPP)
    cd18466
    Location:134 → 236
    BACK_KLHL27_IPP; BACK (BTB and C-terminal Kelch) domain found in intracisternal A particle-promoted polypeptide (IPP)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P28575.3 GenPept UniProtKB/Swiss-Prot:P28575

Gene LinkOut

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