U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C11orf42 chromosome 11 open reading frame 42 [ Homo sapiens (human) ]

Gene ID: 160298, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
C11orf42provided by HGNC
Official Full Name
chromosome 11 open reading frame 42provided by HGNC
Primary source
HGNC:HGNC:28541
See related
Ensembl:ENSG00000180878 AllianceGenome:HGNC:28541
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 2.0), skin (RPKM 0.8) and 18 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C11orf42 in Genome Data Viewer
Location:
11p15.4
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (6205557..6211135)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6264010..6269583)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (6226787..6232365)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 52 subfamily B member 2 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:6206230-6206930 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:6206931-6207629 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:6220268-6220768 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:6220769-6221269 Neighboring gene MPRA-validated peak1185 silencer Neighboring gene olfactory receptor family 52 subfamily W member 1 Neighboring gene FHF complex subunit HOOK interacting protein 1B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3097 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3098 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:6256113-6256803 Neighboring gene cyclic nucleotide gated channel subunit alpha 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. Huttlin EL, et al. Cell, 2015 Jul 16. PMID 26186194, Free PMC Article
  2. Architecture of the human interactome defines protein communities and disease networks. Huttlin EL, et al. Nature, 2017 May 25. PMID 28514442, Free PMC Article
  3. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Huttlin EL, et al. Cell, 2021 May 27. PMID 33961781, Free PMC Article
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC34805

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein C11orf42

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173525.3 → NP_775796.2  uncharacterized protein C11orf42

    See identical proteins and their annotated locations for NP_775796.2

    Status: VALIDATED

    Source sequence(s)
    AA781757, AC022762, BC031612
    Consensus CDS
    CCDS7759.1
    UniProtKB/Swiss-Prot
    Q8N5U0
    Related
    ENSP00000321021.2, ENST00000316375.3
    Conserved Domains (1) summary
    pfam15668
    Location:1 → 328
    DUF4663; Domain of unknown function (DUF4663)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    6205557..6211135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    6264010..6269583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8N5U0.2 GenPept UniProtKB/Swiss-Prot:Q8N5U0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous