Hoxa11os homeobox A11, opposite strand [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Hoxa11osprovided by MGI
Official Full Name: homeobox A11, opposite strandprovided by MGI
Primary source: MGI:MGI:107208
See related: Ensembl:ENSMUSG00000086427 AllianceGenome:MGI:107208
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Hoxa11s; Hoxa11as
Summary: Acts upstream of or within regulation of transcription by RNA polymerase II. Is expressed in several structures, including epidermis; genitourinary system; limb; limb bud; and stomach proventricular region epithelium. Orthologous to human HOXA11-AS (HOXA11 antisense RNA). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in limb E14.5 (RPKM 91.1), colon adult (RPKM 79.9) and 2 other tissues See more
Orthologs: human all
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Genomic context

Location:: 6 B3; 6 25.4 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (52222013..52226770)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (52245243..52249769)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis.
Title: The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis.
LncRNA HOXA11-AS promotes vascular endothelial cell injury in atherosclerosis by regulating the miR-515-5p/ROCK1 axis.
Title: LncRNA HOXA11-AS promotes vascular endothelial cell injury in atherosclerosis by regulating the miR-515-5p/ROCK1 axis.
Inhibition of long non-coding RNA HOXA11-AS against neuroinflammation in Parkinson's disease model via targeting miR-124-3p mediated FSTL1/NF-kappaB axis.
Title: Inhibition of long non-coding RNA HOXA11-AS against neuroinflammation in Parkinson's disease model via targeting miR-124-3p mediated FSTL1/NF-κB axis.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (3) 1 citation

General gene information

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Markers

Hoxa11s (e-PCR), detects polymorphism
- UniSTS:143363

REN100703 (e-PCR)
- UniSTS:425500

REN100704 (e-PCR)
- UniSTS:425501

REN100705 (e-PCR)
- UniSTS:425502

REN100706 (e-PCR)
- UniSTS:425503

Hoxa11 (e-PCR), detects polymorphism
- UniSTS:536638

PMC186320P1 (e-PCR)
- UniSTS:271696

ECD05496 (e-PCR)
- UniSTS:286560

Other Names

HOXA11 antisense RNA (non-protein coding)
HOXA11 opposite strand RNA (non-protein coding)
Hoxa11 opposite strand transcript (non-protein coding)
homeo box A11, opposite strand transcript

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.