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Grcc10 gene rich cluster, C10 gene [ Mus musculus (house mouse) ]

Gene ID: 14790, updated on 5-Mar-2024

Summary

Official Symbol
Grcc10provided by MGI
Official Full Name
gene rich cluster, C10 geneprovided by MGI
Primary source
MGI:MGI:1315201
See related
Ensembl:ENSMUSG00000072772 AllianceGenome:MGI:1315201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C10; 2310033H05Rik
Summary
Predicted to be involved in several processes, including animal organ development; psychomotor behavior; and regulation of skeletal muscle contraction. Predicted to be located in cytoplasm and nuclear speck. Is expressed in several structures, including alimentary system; brain; forelimb bud; reproductive system; and respiratory system. Human ortholog(s) of this gene implicated in Temtamy syndrome. Orthologous to human C12orf57 (chromosome 12 open reading frame 57). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 205.5), CNS E18 (RPKM 202.8) and 28 other tissues See more
Orthologs
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Genomic context

See Grcc10 in Genome Data Viewer
Location:
6 F2; 6 59.17 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (124716146..124718032, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (124739183..124741069, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4862 Neighboring gene microRNA 200c Neighboring gene protein tyrosine phosphatase, non-receptor type 6 Neighboring gene STARR-positive B cell enhancer ABC_E6486 Neighboring gene U7 small nuclear RNA Neighboring gene STARR-positive B cell enhancer ABC_E8991 Neighboring gene atrophin 1 Neighboring gene STARR-seq mESC enhancer starr_17303

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Potential readthrough

Included gene: Atn1

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in camera-type eye morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in cognition ISO
Inferred from Sequence Orthology
more info
 
involved_in corpus callosum morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in post-embryonic development IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in post-embryonic development ISO
Inferred from Sequence Orthology
more info
 
involved_in psychomotor behavior ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of skeletal muscle contraction ISO
Inferred from Sequence Orthology
more info
 
involved_in third ventricle development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein C10
Names
B-cell receptor-associated protein 37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013535.2NP_038563.1  protein C10

    See identical proteins and their annotated locations for NP_038563.1

    Status: VALIDATED

    Source sequence(s)
    AI836086, AK009591, W84158
    Consensus CDS
    CCDS20525.1
    UniProtKB/Swiss-Prot
    O35127, Q545G8
    Related
    ENSMUSP00000004389.6, ENSMUST00000004389.6
    Conserved Domains (1) summary
    pfam14974
    Location:11113
    P_C10; Protein C10

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    124716146..124718032 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)