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Gnl1 guanine nucleotide binding protein-like 1 [ Mus musculus (house mouse) ]

Gene ID: 14670, updated on 11-Apr-2024

Summary

Official Symbol
Gnl1provided by MGI
Official Full Name
guanine nucleotide binding protein-like 1provided by MGI
Primary source
MGI:MGI:95764
See related
Ensembl:ENSMUSG00000024429 AllianceGenome:MGI:95764
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gnal1; Gna-rs1
Summary
Predicted to enable GTPase activity. Predicted to be involved in cellular response to DNA damage stimulus. Orthologous to human GNL1 (G protein nucleolar 1 (putative)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 37.3), frontal lobe adult (RPKM 30.9) and 28 other tissues See more
Orthologs
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Genomic context

See Gnl1 in Genome Data Viewer
Location:
17 B1; 17 18.82 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36290847..36300354)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35979955..35989462)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family F member 1 Neighboring gene microRNA 877 Neighboring gene STARR-positive B cell enhancer ABC_E8674 Neighboring gene predicted gene, 32655 Neighboring gene proline-rich polypeptide 3 Neighboring gene RIKEN cDNA A930015D03 gene Neighboring gene STARR-positive B cell enhancer ABC_E5609 Neighboring gene STARR-positive B cell enhancer ABC_E8921 Neighboring gene STARR-positive B cell enhancer ABC_E959 Neighboring gene STARR-positive B cell enhancer ABC_E4214 Neighboring gene STARR-positive B cell enhancer ABC_E5610 Neighboring gene STARR-positive B cell enhancer ABC_E9951 Neighboring gene histocompatibility 2, T region locus 24 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:36157683-36157870 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:36160698-36160881 Neighboring gene STARR-positive B cell enhancer ABC_E8675 Neighboring gene histocompatibility 2, T region locus 23

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA damage response ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
guanine nucleotide-binding protein-like 1
Names
GTP-binding protein MMR1
guanine nucleotide binding protein, related sequence 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008136.2NP_032162.2  guanine nucleotide-binding protein-like 1

    See identical proteins and their annotated locations for NP_032162.2

    Status: VALIDATED

    Source sequence(s)
    AC112970, AV338067, BC094391, BM949933
    Consensus CDS
    CCDS37606.1
    UniProtKB/Swiss-Prot
    E9QPZ9, P36916, Q91Z20
    UniProtKB/TrEMBL
    A2VDH5
    Related
    ENSMUSP00000084450.4, ENSMUST00000087200.4
    Conserved Domains (2) summary
    cd01857
    Location:177418
    HSR1_MMR1; A circularly permuted subfamily of the Ras GTPases
    PRK09563
    Location:179516
    rbgA; GTPase YlqF; Reviewed

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    36290847..36300354
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)