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PLEKHA7 pleckstrin homology domain containing A7 [ Homo sapiens (human) ]

Gene ID: 144100, updated on 7-Apr-2024

Summary

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Official Symbol
PLEKHA7provided by HGNC
Official Full Name
pleckstrin homology domain containing A7provided by HGNC
Primary source
HGNC:HGNC:27049
See related
Ensembl:ENSG00000166689 MIM:612686; AllianceGenome:HGNC:27049
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Enables delta-catenin binding activity. Involved in epithelial cell-cell adhesion; pore complex assembly; and zonula adherens maintenance. Located in several cellular components, including centrosome; nucleoplasm; and zonula adherens. Part of pore complex. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in esophagus (RPKM 8.9), duodenum (RPKM 8.8) and 24 other tissues See more
Orthologs
mouse all
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Genomic context

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See PLEKHA7 in Genome Data Viewer
Location:
11p15.2-p15.1
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (16777297..17014414, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (16874672..17111588, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (16798844..17035961, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene SRY-box transcription factor 6 Neighboring gene uncharacterized LOC105376571 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16691079-16691580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16691581-16692082 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16699888-16700416 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16700417-16700944 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:16730412-16730912 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:16730913-16731413 Neighboring gene MPRA-validated peak1219 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4480 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16800297-16801020 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:16801021-16801743 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16802139-16802833 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16802834-16803527 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16803848-16804825 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16812593-16813093 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16812092-16812592 Neighboring gene chromosome 11 open reading frame 58 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:16823697-16824896 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:16836605-16837105 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:16875052-16875264 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4481 Neighboring gene VISTA enhancer hs2096 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:16918881-16919566 Neighboring gene RN7SK pseudogene 90 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:16946213-16946824 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:16957385-16957896 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4482 Neighboring gene uncharacterized LOC124902817 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:17003172-17003810 Neighboring gene small nucleolar RNA, C/D box 147 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4483 Neighboring gene Sharpr-MPRA regulatory region 14902 Neighboring gene ribosomal protein L36a pseudogene 37 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:17043091-17043592 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:17058129-17058705 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:17058706-17059281 Neighboring gene small nucleolar RNA, C/D box 14A Neighboring gene olfactory receptor family 7 subfamily E member 14 pseudogene Neighboring gene ribosomal protein S13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer. Jeung HC, et al. Exp Cell Res, 2021 Dec 15. PMID 34800542, Free PMC Article
  2. Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids. Aleshin AE, et al. Structure, 2021 Sep 2. PMID 33878292, Free PMC Article
  3. The Expression of the Zonula Adhaerens Protein PLEKHA7 Is Strongly Decreased in High Grade Ductal and Lobular Breast Carcinomas. Tille JC, et al. PLoS One, 2015. PMID 26270346, Free PMC Article
  4. Expression of the primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 in endothelial and epithelial cell junctions in the eye. Lee MC, et al. Invest Ophthalmol Vis Sci, 2014 May 6. PMID 24801512
  5. Genetic up-regulation and overexpression of PLEKHA7 differentiates invasive lobular carcinomas from invasive ductal carcinomas. Castellana B, et al. Hum Pathol, 2012 Nov. PMID 22542108

See all (77) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis.
    Title: The hTERT-p50 homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis.
  2. The PLEKHA7-PDZD11 complex regulates the localization of the calcium pump PMCA and calcium handling in cultured cells.
    Title: The PLEKHA7-PDZD11 complex regulates the localization of the calcium pump PMCA and calcium handling in cultured cells.
  3. PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis.
    Title: PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis.
  4. Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
    Title: Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
  5. PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.
    Title: PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.
  6. PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression.
    Title: PLEKHA7, an Apical Adherens Junction Protein, Suppresses Inflammatory Breast Cancer in the Context of High E-Cadherin and p120-Catenin Expression.
  7. Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33.
    Title: Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33.
  8. Downregulation of PLEKHA7 in PACG may affect BAB integrity and aqueous humor outflow via its Rac1/Cdc42 GAP activity, thereby contributing to disease etiology.
    Title: Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function.
  9. our findings support a multi-layered role of PLEKHA7 in converging cytoskeletal dynamics and miRNA-mediated growth regulation at the ZA, with potentially critical implications in cancer that warrant further investigation.
    Title: PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications.
  10. These results show that the PLEKHA7-PDZD11 complex stabilizes nectins to promote efficient early junction assembly and uncover a new molecular mechanism through which PLEKHA7 recruits PDZ-binding membrane proteins to epithelial adherens junctions.
    Title: PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.
Submit: New GeneRIF Correction See all GeneRIFs (29)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.
EBI GWAS Catalog
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
EBI GWAS Catalog
Genome-wide association study of blood pressure and hypertension.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • DKFZp686B1134, DKFZp686M2234, DKFZp686M22243

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables delta-catenin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion mediated by cadherin IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell-cell adhesion mediated by cadherin ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in epithelial cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in epithelial cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pore complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pore complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in zonula adherens maintenance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in zonula adherens maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell junction IDA
Inferred from Direct Assay
more info
  
located_in centrosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in extracellular exosome HDA PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
part_of pore complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of pore complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
is_active_in zonula adherens IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in zonula adherens IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family A member 7
Names
PH domain-containing family A member 7
pleckstrin homology domain containing, family A member 2
pleckstrin homology domain containing, family A member 7
pleckstrin homology domain-containing family A member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001329630.2 → NP_001316559.1  pleckstrin homology domain-containing family A member 7 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC026639, AC127033, BC032761, BC071599, BE873160, CN293588, DR731351
    Consensus CDS
    CCDS86182.1
    UniProtKB/TrEMBL
    A0A1B0GTN9, E9PKC0
    Related
    ENSP00000435389.1, ENST00000531066.6
    Conserved Domains (5) summary
    pfam06390
    Location:299 → 460
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:159 → 281
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00169
    Location:165 → 280
    PH; PH domain
    pfam00397
    Location:56 → 85
    WW; WW domain
    pfam07798
    Location:712 → 838
    DUF1640; Protein of unknown function (DUF1640)

  2. NM_001329631.2 → NP_001316560.1  pleckstrin homology domain-containing family A member 7 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, lacks several exons, and its 3'-terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC026639, AC116533, AC127033
    UniProtKB/TrEMBL
    A0A8Q3WLI9

  3. NM_001410960.1 → NP_001397889.1  pleckstrin homology domain-containing family A member 7 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC026639, AC116533, AC127033
    Consensus CDS
    CCDS91448.1
    UniProtKB/TrEMBL
    A0A8V8TMS3
    Related
    ENSP00000513972.1, ENST00000698836.1

  4. NM_175058.5 → NP_778228.3  pleckstrin homology domain-containing family A member 7 isoform 2

    See identical proteins and their annotated locations for NP_778228.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks several exons, and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC026639, AC127033, AW135567, BC071599, CN293588
    Consensus CDS
    CCDS31434.1
    UniProtKB/Swiss-Prot
    B4DK33, B4DWC3, Q6IQ23, Q86VZ7
    UniProtKB/TrEMBL
    A0A8Q3WLI9
    Related
    ENSP00000347883.2, ENST00000355661.7
    Conserved Domains (6) summary
    pfam06390
    Location:299 → 460
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd00890
    Location:656 → 743
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cd13248
    Location:159 → 281
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00169
    Location:165 → 280
    PH; PH domain
    pfam00397
    Location:56 → 85
    WW; WW domain
    pfam07798
    Location:712 → 838
    DUF1640; Protein of unknown function (DUF1640)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    16777297..17014414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426441.1 → XP_047282397.1  pleckstrin homology domain-containing family A member 7 isoform X24

  2. XM_047426436.1 → XP_047282392.1  pleckstrin homology domain-containing family A member 7 isoform X17

  3. XM_047426430.1 → XP_047282386.1  pleckstrin homology domain-containing family A member 7 isoform X7

  4. XM_047426429.1 → XP_047282385.1  pleckstrin homology domain-containing family A member 7 isoform X6

  5. XM_024448358.2 → XP_024304126.1  pleckstrin homology domain-containing family A member 7 isoform X3

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (4) summary
    pfam06390
    Location:299 → 460
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:159 → 281
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00397
    Location:56 → 85
    WW; WW domain
    pfam07798
    Location:779 → 905
    DUF1640; Protein of unknown function (DUF1640)

  6. XM_047426439.1 → XP_047282395.1  pleckstrin homology domain-containing family A member 7 isoform X22

  7. XM_047426435.1 → XP_047282391.1  pleckstrin homology domain-containing family A member 7 isoform X16

  8. XM_047426432.1 → XP_047282388.1  pleckstrin homology domain-containing family A member 7 isoform X9

  9. XM_047426431.1 → XP_047282387.1  pleckstrin homology domain-containing family A member 7 isoform X8

  10. XM_047426428.1 → XP_047282384.1  pleckstrin homology domain-containing family A member 7 isoform X5

  11. XM_047426427.1 → XP_047282383.1  pleckstrin homology domain-containing family A member 7 isoform X4

  12. XM_024448370.2 → XP_024304138.1  pleckstrin homology domain-containing family A member 7 isoform X13

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (4) summary
    pfam06390
    Location:299 → 460
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:159 → 281
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00397
    Location:56 → 85
    WW; WW domain
    pfam07798
    Location:779 → 865
    DUF1640; Protein of unknown function (DUF1640)

  13. XM_024448357.2 → XP_024304125.1  pleckstrin homology domain-containing family A member 7 isoform X2

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (4) summary
    pfam06390
    Location:299 → 460
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:159 → 281
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam00397
    Location:56 → 85
    WW; WW domain
    pfam07798
    Location:779 → 905
    DUF1640; Protein of unknown function (DUF1640)

  14. XM_047426426.1 → XP_047282382.1  pleckstrin homology domain-containing family A member 7 isoform X1

  15. XM_047426437.1 → XP_047282393.1  pleckstrin homology domain-containing family A member 7 isoform X19

  16. XM_047426434.1 → XP_047282390.1  pleckstrin homology domain-containing family A member 7 isoform X14

  17. XM_024448361.2 → XP_024304129.1  pleckstrin homology domain-containing family A member 7 isoform X11

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (2) summary
    cd13248
    Location:113 → 235
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam07798
    Location:733 → 859
    DUF1640; Protein of unknown function (DUF1640)

  18. XM_047426433.1 → XP_047282389.1  pleckstrin homology domain-containing family A member 7 isoform X10

  19. XM_024448367.2 → XP_024304135.1  pleckstrin homology domain-containing family A member 7 isoform X18

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (3) summary
    pfam06390
    Location:193 → 354
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:53 → 175
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam07798
    Location:673 → 799
    DUF1640; Protein of unknown function (DUF1640)

  20. XM_024448366.2 → XP_024304134.1  pleckstrin homology domain-containing family A member 7 isoform X18

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (3) summary
    pfam06390
    Location:193 → 354
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:53 → 175
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam07798
    Location:673 → 799
    DUF1640; Protein of unknown function (DUF1640)

  21. XM_024448362.2 → XP_024304130.1  pleckstrin homology domain-containing family A member 7 isoform X12

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (3) summary
    pfam06390
    Location:241 → 402
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:101 → 223
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam07798
    Location:721 → 847
    DUF1640; Protein of unknown function (DUF1640)

  22. XM_024448369.2 → XP_024304137.1  pleckstrin homology domain-containing family A member 7 isoform X18

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Conserved Domains (3) summary
    pfam06390
    Location:193 → 354
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:53 → 175
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam07798
    Location:673 → 799
    DUF1640; Protein of unknown function (DUF1640)

  23. XM_024448365.2 → XP_024304133.1  pleckstrin homology domain-containing family A member 7 isoform X15

    UniProtKB/TrEMBL
    A0A1B0GTN9
    Related
    ENSP00000489780.1, ENST00000637162.1
    Conserved Domains (3) summary
    pfam06390
    Location:205 → 366
    NESP55; Neuroendocrine-specific golgi protein P55 (NESP55)
    cd13248
    Location:65 → 187
    PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    pfam07798
    Location:685 → 811
    DUF1640; Protein of unknown function (DUF1640)

  24. XM_047426438.1 → XP_047282394.1  pleckstrin homology domain-containing family A member 7 isoform X20

  25. XM_047426444.1 → XP_047282400.1  pleckstrin homology domain-containing family A member 7 isoform X28

  26. XM_017017242.3 → XP_016872731.1  pleckstrin homology domain-containing family A member 7 isoform X25

    UniProtKB/TrEMBL
    A0A8Q3WLI9

  27. XM_047426440.1 → XP_047282396.1  pleckstrin homology domain-containing family A member 7 isoform X23

  28. XM_017017241.3 → XP_016872730.1  pleckstrin homology domain-containing family A member 7 isoform X21

    UniProtKB/TrEMBL
    A0A8Q3WLI9

  29. XM_047426447.1 → XP_047282403.1  pleckstrin homology domain-containing family A member 7 isoform X31

  30. XM_047426443.1 → XP_047282399.1  pleckstrin homology domain-containing family A member 7 isoform X27

    Related
    ENSP00000512848.1, ENST00000696749.1

  31. XM_047426442.1 → XP_047282398.1  pleckstrin homology domain-containing family A member 7 isoform X26

  32. XM_047426446.1 → XP_047282402.1  pleckstrin homology domain-containing family A member 7 isoform X30

  33. XM_047426445.1 → XP_047282401.1  pleckstrin homology domain-containing family A member 7 isoform X29

RNA

  1. XR_007062454.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    16874672..17111588 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054367802.1 → XP_054223777.1  pleckstrin homology domain-containing family A member 7 isoform X24

  2. XM_054367792.1 → XP_054223767.1  pleckstrin homology domain-containing family A member 7 isoform X17

  3. XM_054367782.1 → XP_054223757.1  pleckstrin homology domain-containing family A member 7 isoform X7

  4. XM_054367781.1 → XP_054223756.1  pleckstrin homology domain-containing family A member 7 isoform X6

  5. XM_054367778.1 → XP_054223753.1  pleckstrin homology domain-containing family A member 7 isoform X3

  6. XM_054367791.1 → XP_054223766.1  pleckstrin homology domain-containing family A member 7 isoform X16

  7. XM_054367800.1 → XP_054223775.1  pleckstrin homology domain-containing family A member 7 isoform X22

  8. XM_054367784.1 → XP_054223759.1  pleckstrin homology domain-containing family A member 7 isoform X9

  9. XM_054367783.1 → XP_054223758.1  pleckstrin homology domain-containing family A member 7 isoform X8

  10. XM_054367780.1 → XP_054223755.1  pleckstrin homology domain-containing family A member 7 isoform X5

  11. XM_054367779.1 → XP_054223754.1  pleckstrin homology domain-containing family A member 7 isoform X4

  12. XM_054367788.1 → XP_054223763.1  pleckstrin homology domain-containing family A member 7 isoform X13

  13. XM_054367777.1 → XP_054223752.1  pleckstrin homology domain-containing family A member 7 isoform X2

  14. XM_054367776.1 → XP_054223751.1  pleckstrin homology domain-containing family A member 7 isoform X1

  15. XM_054367786.1 → XP_054223761.1  pleckstrin homology domain-containing family A member 7 isoform X11

  16. XM_054367789.1 → XP_054223764.1  pleckstrin homology domain-containing family A member 7 isoform X14

  17. XM_054367797.1 → XP_054223772.1  pleckstrin homology domain-containing family A member 7 isoform X19

  18. XM_054367795.1 → XP_054223770.1  pleckstrin homology domain-containing family A member 7 isoform X18

  19. XM_054367785.1 → XP_054223760.1  pleckstrin homology domain-containing family A member 7 isoform X10

  20. XM_054367794.1 → XP_054223769.1  pleckstrin homology domain-containing family A member 7 isoform X18

  21. XM_054367793.1 → XP_054223768.1  pleckstrin homology domain-containing family A member 7 isoform X18

  22. XM_054367787.1 → XP_054223762.1  pleckstrin homology domain-containing family A member 7 isoform X12

  23. XM_054367796.1 → XP_054223771.1  pleckstrin homology domain-containing family A member 7 isoform X18

  24. XM_054367790.1 → XP_054223765.1  pleckstrin homology domain-containing family A member 7 isoform X15

  25. XM_054367798.1 → XP_054223773.1  pleckstrin homology domain-containing family A member 7 isoform X20

  26. XM_054367806.1 → XP_054223781.1  pleckstrin homology domain-containing family A member 7 isoform X28

  27. XM_054367803.1 → XP_054223778.1  pleckstrin homology domain-containing family A member 7 isoform X25

  28. XM_054367801.1 → XP_054223776.1  pleckstrin homology domain-containing family A member 7 isoform X23

  29. XM_054367799.1 → XP_054223774.1  pleckstrin homology domain-containing family A member 7 isoform X21

  30. XM_054367809.1 → XP_054223784.1  pleckstrin homology domain-containing family A member 7 isoform X31

  31. XM_054367805.1 → XP_054223780.1  pleckstrin homology domain-containing family A member 7 isoform X27

  32. XM_054367804.1 → XP_054223779.1  pleckstrin homology domain-containing family A member 7 isoform X26

  33. XM_054367808.1 → XP_054223783.1  pleckstrin homology domain-containing family A member 7 isoform X30

  34. XM_054367807.1 → XP_054223782.1  pleckstrin homology domain-containing family A member 7 isoform X29

RNA

  1. XR_008488346.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IQ23.2 GenPept UniProtKB/Swiss-Prot:Q6IQ23

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