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ARB2BP ARB2 family member B, pseudogene [ Homo sapiens (human) ]

Gene ID: 131909, updated on 23-Nov-2023

Summary

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Official Symbol
ARB2BPprovided by HGNC
Official Full Name
ARB2 family member B, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:34336
See related
AllianceGenome:HGNC:34336
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM172B; FAM172BP
Summary
Predicted to contribute to siRNA binding activity. Predicted to be involved in heterochromatin assembly by small RNA. Predicted to be integral component of membrane. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
3q12.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (101518867..101523887)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (104225133..104230152)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (101237711..101242731)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene SUMO specific peptidase 7 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:101185392-101185939 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:101185940-101186486 Neighboring gene basic transcription factor 3 pseudogene 16 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr3:101203214-101204413 Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20164 Neighboring gene CRISPRi-validated cis-regulatory element chr3.3097 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:101274853-101275465 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20165 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20166 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:101292235-101293180 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20169 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20170 Neighboring gene tRNA methyltransferase 10C, mitochondrial RNase P subunit Neighboring gene ribosomal protein S18 pseudogene 5 Neighboring gene PEST proteolytic signal containing nuclear protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • family with sequence similarity 172 member B, pseudogene

Clone Names

  • FLJ45679

Gene Ontology Provided by GOA

Function Evidence Code Pubs
contributes_to siRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulatory ncRNA-mediated heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036433.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC073861

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    101518867..101523887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    104225133..104230152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_008062.1: Suppressed sequence

    Description
    NG_008062.1: This RefSeq was permanently suppressed because there is sufficient evidence that this locus is transcribed.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A6NC97.3 GenPept UniProtKB/Swiss-Prot:A6NC97

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials