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LOC127896558 H3K4me1 hESC enhancer GRCh37_chr22:43883837-43884610 [ Homo sapiens (human) ]

Gene ID: 127896558, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127896558
Gene description
H3K4me1 hESC enhancer GRCh37_chr22:43883837-43884610
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (43487957..43488730)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (43970704..43971477)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373053 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:43784068-43784646 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:43784647-43785225 Neighboring gene long intergenic non-protein coding RNA 1639 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43823805-43824306 Neighboring gene metallophosphoesterase domain containing 1 Neighboring gene MPRA-validated peak4505 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43860857-43861358 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43883063-43883836 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43910482-43911240 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:43923573-43924072 Neighboring gene EFCAB6 antisense RNA 1 Neighboring gene NANOG hESC enhancer GRCh37_chr22:43932755-43933256 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43938541-43939320 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43939321-43940098 Neighboring gene EF-hand calcium binding domain 6 Neighboring gene uncharacterized LOC101927474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43966769-43967269

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_146080.1 

    Range
    101..874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    43487957..43488730
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    43970704..43971477
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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