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LOC127896532 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:43593145-43594077 [ Homo sapiens (human) ]

Gene ID: 127896532, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127896532
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:43593145-43594077
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127896532 in Genome Data Viewer
Location:
chromosome: 22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (43197139..43198071)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (43678007..43678939)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19186 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43553089-43553609 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43559052-43559555 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43559556-43560058 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43564214-43565070 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43565071-43565926 Neighboring gene translocator protein Neighboring gene tubulin tyrosine ligase like 12 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:43581791-43582295 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19188 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13857 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13858 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13859 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:43594078-43595009 Neighboring gene signal peptide, CUB domain and EGF like domain containing 1 Neighboring gene SCUBE1 antisense RNA 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43616253-43616754 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:43621086-43621251 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43621872-43622438 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43622439-43623004 Neighboring gene Sharpr-MPRA regulatory region 15411 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43634226-43634726 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:43634727-43635227 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:43643537-43644038 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:43647561-43647749 Neighboring gene uncharacterized LOC124905129 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr22:43659412-43660611

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_146056.1 

    Range
    101..1033
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    43197139..43198071
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    43678007..43678939
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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