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LOC127830084 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:72939289-72940171 [ Homo sapiens (human) ]

Gene ID: 127830084, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127830084
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:72939289-72940171
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (72646948..72647830)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (70464262..70465144)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene SWI5 recombination repair homolog (yeast) pseudogene Neighboring gene golgin A6 family member A pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:72902139-72902639 Neighboring gene long intergenic non-protein coding RNA 2259 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9725 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9726 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:72920983-72921575 Neighboring gene uncharacterized LOC112268145 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr15:72942597-72943114 Neighboring gene golgin A6 family member B Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:72954615-72955116 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:72955117-72955616 Neighboring gene RNA, 7SL, cytoplasmic 853, pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:72963099-72964076 Neighboring gene HIG1 hypoxia inducible domain family member 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_131566.1 

    Range
    101..983
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    72646948..72647830
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    70464262..70465144
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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