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LOC127829678 H3K27ac hESC enhancer GRCh37_chr15:62982679-62983533 [ Homo sapiens (human) ]

Gene ID: 127829678, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127829678
Gene description
H3K27ac hESC enhancer GRCh37_chr15:62982679-62983533
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (62690480..62691334)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (60493985..60494834)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene talin 2 Neighboring gene uncharacterized LOC105370855 Neighboring gene uncharacterized protein MGC15885 Neighboring gene Sharpr-MPRA regulatory region 9569 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63000369-63001140 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63014118-63014618 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63014619-63015119 Neighboring gene ReSE screen-validated silencer GRCh37_chr15:63035758-63035913 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr15:63050295-63051092 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:63051093-63051890 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:63062481-63062994 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63074305-63075233 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63088457-63088957 Neighboring gene uncharacterized LOC105370854 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:63126856-63128055 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63137585-63138085 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63138767-63139268 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63139269-63139768 Neighboring gene microRNA 190a Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:63167575-63168413

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_131160.1 

    Range
    101..955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    62690480..62691334
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    60493985..60494834
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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