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LOC127822377 H3K4me1 hESC enhancer GRCh37_chr11:94883489-94884030 [ Homo sapiens (human) ]

Gene ID: 127822377, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127822377
Gene description
H3K4me1 hESC enhancer GRCh37_chr11:94883489-94884030
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (95150325..95150866)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (95157444..95157985)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3846 Neighboring gene Sharpr-MPRA regulatory region 7470 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5414 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:94841280-94842479 Neighboring gene endonuclease domain containing 1 Neighboring gene CRISPRi-validated cis-regulatory element chr11.4868 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:94884031-94884572 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3847 Neighboring gene lncRNA imatinib upregulated Neighboring gene BUD13 homolog pseudogene 1 Neighboring gene sestrin 3 Neighboring gene uncharacterized LOC100129203 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3849 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:94964745-94965384 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:94965385-94966024 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:94981794-94982294 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5416 Neighboring gene Sharpr-MPRA regulatory region 282 Neighboring gene VISTA enhancer hs2531 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:95074595-95075094 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:95092304-95093503 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3850 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:95180437-95180967 Neighboring gene uncharacterized LOC105369439 Neighboring gene MPRA-validated peak1408 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr11:95209557-95210058

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_123819.1 

    Range
    101..642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    95150325..95150866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    95157444..95157985
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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