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LOC127817816 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:43850991-43851698 [ Homo sapiens (human) ]

Gene ID: 127817816, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127817816
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:43850991-43851698
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (43355543..43356250)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (44234513..44235221)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378271 Neighboring gene RNA, U6atac small nuclear 11, pseudogene Neighboring gene uncharacterized LOC107984226 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2325 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:43857038-43857950 Neighboring gene FXYD domain containing ion transport regulator 4 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2326 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3290 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3291 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3292 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:43882175-43882676 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:43882677-43883176 Neighboring gene heterogeneous nuclear ribonucleoprotein F Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:43890785-43891672 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3293 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2327 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:43893449-43894334 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3294 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:43897064-43897583 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2328 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3295 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:43903361-43903964 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2329 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3298

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_119292.1 

    Range
    101..808
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    43355543..43356250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    44234513..44235221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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