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LOC127817356 OCT4-NANOG hESC enhancer GRCh37_chr10:20661486-20662107 [ Homo sapiens (human) ]

Gene ID: 127817356, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127817356
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr10:20661486-20662107
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (20372557..20373178)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (20390943..20391564)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene plexin domain containing 2 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:20208919-20209420 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3117 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3118 Neighboring gene NANOG hESC enhancer GRCh37_chr10:20408149-20408686 Neighboring gene NANOG hESC enhancer GRCh37_chr10:20413464-20413975 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:20546341-20546868 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:20659563-20660207 Neighboring gene adenosylmethionine decarboxylase 1 pseudogene 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:20716465-20716965 Neighboring gene uncharacterized LOC105376442 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:20885982-20886482 Neighboring gene microRNA 4675

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_118836.1 

    Range
    101..722
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    20372557..20373178
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    20390943..20391564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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