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LOC127815862 NANOG-H3K4me1 hESC enhancer GRCh37_chr9:126666093-126666593 [ Homo sapiens (human) ]

Gene ID: 127815862, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127815862
Gene description
NANOG-H3K4me1 hESC enhancer GRCh37_chr9:126666093-126666593
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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Location:
chromosome: 9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (123903814..123904314)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (136101701..136102201)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene DENN domain containing 1A Neighboring gene uncharacterized LOC124902336 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:126625148-126625690 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:126625691-126626232 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class F pseudogene 2 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:126656962-126657562 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr9:126665592-126666092 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28952 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28953 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:126691277-126691962 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20252 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:126755411-126755911 Neighboring gene uncharacterized LOC105376267 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28956 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:126760357-126761111 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20253 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20254 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:126763235-126763735 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr9:126767105-126767862 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:126769682-126770393 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:126770394-126771104 Neighboring gene LHX2 antisense RNA 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_117367.1 

    Range
    101..601
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    123903814..123904314
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    136101701..136102201
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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