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LOC127457290 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:101937369-101938122 [ Homo sapiens (human) ]

Gene ID: 127457290, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127457290
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:101937369-101938122
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127457290 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (102294104..102294857)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (103611481..103612234)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene cut like homeobox 1 Neighboring gene uncharacterized LOC124901711 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:101911196-101911353 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101917405-101918238 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101922504-101923122 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101923123-101923741 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:101927516-101927700 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18499 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18500 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26421 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18501 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26423 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26422 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:101949043-101949828 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26425 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:101951399-101952183 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101957283-101957934 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101957935-101958585 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101959159-101959659 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101960288-101961000 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:101962426-101963137 Neighboring gene uncharacterized LOC107986717 Neighboring gene microRNA 4285 Neighboring gene SH2B adaptor protein 2 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_112064.1 

    Range
    101..854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    102294104..102294857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    103611481..103612234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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