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LOC127409009 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:44253740-44254655 [ Homo sapiens (human) ]

Gene ID: 127409009, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127409009
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:44253740-44254655
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (44214141..44215056)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (44372728..44373643)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375258 Neighboring gene uncharacterized LOC105375257 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44223563-44224100 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44224101-44224636 Neighboring gene glucokinase Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18143 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:44257065-44257612 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:44257613-44258158 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44260592-44261156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44261157-44261720 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44275325-44276208 Neighboring gene YKT6 v-SNARE homolog Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25933 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25934 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25935 Neighboring gene calcium/calmodulin dependent protein kinase II beta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44289329-44289847 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25936 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25937 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44301759-44302258 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44302657-44303488 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44303489-44304320 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44307207-44307708 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44307709-44308208 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44311666-44312166 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44322903-44323685 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44328206-44328848 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44329545-44330046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44333819-44334319 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25938 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:44348485-44349088 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:44349089-44349690 Neighboring gene uncharacterized LOC124901621 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25939 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:44389311-44389811 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25940 Neighboring gene NudC domain containing 3 Neighboring gene ribosomal protein L32 pseudogene 18

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_110975.1 

    Range
    101..1016
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    44214141..44215056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    44372728..44373643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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